Figure 6

Longitudinal analysis of TL in CD4⁺virus-specific memory T cells. (A) TL was measured in CD4⁺ BrdU^- CD45RA⁺ (dotted lines) and CD4⁺ BrdU+ T cells (solid lines) from five healthy subjects. PBMC samples were obtained 8 to 10 years apart. (B) The data from A were grouped according to different virus-specific T cell populations for all 5 subjects. Dotted lines are derived from the average slopes and y-intercepts. (C) Average TL kinetic of each virus-specific T cell population and naïve T cell average TL line from each plot in B is presented as single plot to allow comparisons of the average T cell TL kinetics in this cohort of healthy adults.