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Table 3 Glycan epitope pattern of Cy5 labeled ACT

From: Altered glycosylation profile of purified plasma ACT from Alzheimer’s disease

Glycan epitope

CTR 1

AD 1

CTR 2

AD 2

N-linked:

    

Bi Antennary

Not Detected

Not Detected

Not Detected

Not Detected

Tri/Tetra Antennary

High

High

High

High

High Mannose

Not Detected

Not Detected

Not Detected

Not Detected

Sialic Acid

High

Medium

High

Medium

Terminal GlcNAc

Low

Low

Low

Not Detected

Terminal GalNAc

Not Detected

Not Detected

Not Detected

Not Detected

Bisecting GlcNAc

Not Detected

Not Detected

Not Detected

Not Detected

O-Glycans

Not Detected

Not Detected

Not Detected

Not Detected

  1. Glycan profile produced for ACT using the Qproteome Glycoarray method.
  2. ND=not detected (up to 10%); Low=11-30%; Medium=31-70%; High=71-100%