Figure 3
From: An adjuvanted respiratory syncytial virus fusion protein induces protection in aged BALB/c mice
Cytokine levels in the lung homogenates. Cytokines and chemokines in lung homogenates isolated 4 days post-challenge were measured using a 15-plex bead array panel (Luminex). Shown are representative TH1 (IFNγ), TH2 (IL-5) cytokines, and eotaxin levels. (A) IFNγ levels. *, P < 0.05 comparing RSV to placebo, F, or F + alum in young mice (ANOVA). #, P < 0.05 comparing RSV to placebo, F, or F + alum in aged mice (ANOVA). (B) IL-5 levels. *, P < 0.05 comparing F to F + alum in young mice (ANOVA). (C) Eotaxin levels. *, P < 0.05 comparing RSV to placebo, F, or F + alum in young mice (ANOVA).