Table 3 Characteristics of patients in the study, divided by positivity for serotypes
Total n = 417 | Negative n = 376 | Positive only for PCV13 serotypes n = 6 | Positive for PCV13 and non-PCV13 serotypes n = 28 | Positive only for non-PCV13 serotypes n = 6 | ||
|---|---|---|---|---|---|---|
Age | <75 years | 246 (58.99) | 218 (57.82) | 5 (83.33) | 20 (71.43) | 3 (50) |
> = 75 years | 171 (41.01) | 159 (42.18) | 1 (16.67) | 8 (28.57) | 3 (50) | |
Mean age (sd) | 73.97 (6.66) | 74.18 (6.7) | 69.83 (3.92) | 72.32 (6.57) | 72.5 (5.01) | |
Sex | Male | 115 (27.58) | 106 (28.12) | 2 (33.33) | 4 (14.29) | 3 (50) |
Female | 302 (72.42) | 271 (71.88) | 4 (66.67) | 24 (85.71) | 3 (50) | |
Ethnicity | Caucasian | 403 (96.64) | 367 (97.35) | 6 (100) | 24 (85.71) | 6 (100) |
Non-Caucasian | 10 (2.4) | 8 (2.12) | 0 (0) | 2 (7.14) | 0 (0) | |
NA | 4 (0.96) | 2 (0.53) | 0 (0) | 2 (7.14) | 0 (0) | |
Mean number of cohabitants (sd) | 401 (96.16) | 362 (96.02) | 6 (100) | 27 (96.43) | 6 (100) | |
Children cohabitants | No | 0.22 (0.55) | 0.23 (0.56) | 0 (0) | 0.12 (0.44) | 0.17 (0.41) |
Yes | 2 (0.48) | 2 (0.53) | 0 (0) | 0 (0) | 0 (0) | |
NA | 14 (3.36) | 13 (3.45) | 0 (0) | 1 (3.57) | 0 (0) | |
Nephew | No | 195 (46.76) | 180 (47.75) | 1 (16.67) | 11 (39.29) | 3 (50) |
Yes | 89 (21.34) | 82 (21.75) | 1 (16.67) | 4 (14.29) | 2 (33.33) | |
NA | 133 (31.89) | 115 (30.5) | 4 (66.67) | 13 (46.43) | 1 (16.67) | |
Marital status | Married/Cohabiting | 223 (53.48) | 200 (53.05) | 4 (66.67) | 15 (53.57) | 4 (66.67) |
Single | 57 (13.67) | 52 (13.79) | 1 (16.67) | 4 (14.29) | 0 (0) | |
Separated | 53 (12.71) | 48 (12.73) | 1 (16.67) | 3 (10.71) | 1 (16.67) | |
Widowed | 83 (19.9) | 76 (20.16) | 0 (0) | 6 (21.43) | 1 (16.67) | |
NA | 1 (0.24) | 1 (0.27) | 0 (0) | 0 (0) | 0 (0) | |
Smoker | No | 367 (88.01) | 332 (88.06) | 5 (83.33) | 25 (89.29) | 5 (83.33) |
Yes | 49 (11.75) | 44 (11.67) | 1 (16.67) | 3 (10.71) | 1 (16.67) | |
NA | 1 (0.24) | 1 (0.27) | 0 (0) | 0 (0) | 0 (0) | |
Respiratory allergies | No | 291 (69.78) | 266 (70.56) | 6 (100) | 17 (60.71) | 2 (33.33) |
Yes | 126 (30.22) | 111 (29.44) | 0 (0) | 11 (39.29) | 4 (66.67) | |
Co-morbidities | No | 137 (32.85) | 117 (31.03) | 3 (50) | 17 (60.71) | 0 (0) |
Yes | 278 (66.67) | 259 (68.7) | 3 (50) | 10 (35.71) | 6 (100) | |
NA | 2 (0.48) | 1 (0.27) | 0 (0) | 1 (3.57) | 0 (0) | |
Group of co-morbidities | Respiratory | 86 (20.62) | 80 (21.22) | 0 (0) | 3 (10.71) | 3 (50) |
Cardiac | 120 (28.78) | 114 (30.24) | 1 (16.67) | 4 (14.29) | 1 (16.67) | |
Metabolic | 23 (5.52) | 20 (5.31) | 1 (16.67) | 1 (3.57) | 1 (16.67) | |
Tumours | 10 (2.4) | 10 (2.65) | 0 (0) | 0 (0) | 0 (0) | |
Thyroid | 23 (5.52) | 20 (5.31) | 1 (16.67) | 2 (7.14) | 0 (0) | |
Other | 16 (3.84) | 15 (3.98) | 0 (0) | 0 (0) | 1 (16.67) | |
None | 137 (32.85) | 117 (31.03) | 3 (50) | 17 (60.71) | 0 (0) | |
NA | 2 (0.48) | 1 (0.27) | 0 (0) | 1 (3.57) | 0 (0) | |
Pneumococcal vaccination | No | 389 (93.29) | 350 (92.84) | 6 (100) | 28 (100) | 5 (83.33) |
Yes | 28 (6.71) | 27 (7.16) | 0 (0) | 0 (0) | 1 (16.67) | |
Type of vaccination | PCV13 | 10 (2.4) | 10 (2.65) | 0 (0) | 0 (0) | 0 (0) |
PPV23 | 17 (4.08) | 16 (4.24) | 0 (0) | 0 (0) | 1 (16.67) | |
NA | 390 (93.53) | 351 (93.1) | 6 (100) | 28 (100) | 5 (83.33) | |
Influenza vaccination | No | 215 (51.56) | 191 (50.66) | 4 (66.67) | 16 (57.14) | 4 (66.67) |
Yes | 202 (48.44) | 186 (49.34) | 2 (33.33) | 12 (42.86) | 2 (33.33) | |
Mean number of respiratory infections (sd) | 0.9 (1.87) | 0.89 (1.91) | 1.4 (1.14) | 0.92 (1.04) | 1 (2.45) | |
Mean number of upper respiratory tract infections (sd) | 0.61 (1.64) | 0.6 (1.67) | 1 (1.22) | 0.65 (0.98) | 1 (2.45) | |
Mean number of lower respiratory tract infections (sd) | 0.28 (0.68) | 0.29 (0.69) | 0.4 (0.55) | 0.24 (0.52) | 0 (0) | |
Hospitalizations in the last 3 months | No | 404 (96.88) | 364 (96.55) | 6 (100) | 28 (100) | 6 (100) |
Yes | 13 (3.12) | 13 (3.45) | 0 (0) | 0 (0) | 0 (0) | |
Emergency Room visit in the last 3 months | No | 388 (93.05) | 352 (93.37) | 5 (83.33) | 25 (89.29) | 6 (100) |
Yes | 24 (5.76) | 22 (5.84) | 0 (0) | 2 (7.14) | 0 (0) | |
NA | 5 (1.2) | 3 (0.8) | 1 (16.67) | 1 (3.57) | 0 (0) | |
Treatments with antibiotic in the last month | No | 368 (88.25) | 329 (87.27) | 6 (100) | 27 (96.43) | 6 (100) |
Yes | 49 (11.75) | 48 (12.73) | 0 (0) | 1 (3.57) | 0 (0) | |
Pneumococcal infections in the last month | No | 363 (87.05) | 327 (86.74) | 6 (100) | 24 (85.71) | 6 (100) |
Yes | 54 (12.95) | 50 (13.26) | 0 (0) | 4 (14.29) | 0 (0) | |