Table 2 Markers of cell damage, neutrophil, and macrophage activation in patients with different outcome

Alu 115 (n-cfDNA ) pg/μl^a, median(IQR)

361.7 (154.2-1041.9)

340.3 (163.9-1036.3)

385.2 (145.5-1109.1)

0.953

Alu 247 (n-cfDNA) pg/μl^a, median(IQR)

136.9 (52.6-519.8)

163.4 (51.9-719.2)

109.7 (53.3-378.0)

0.449

Alu 247/115 (n-cfDNA integrity), median(IQR)

0.44 (0.33-0.77)

0.50 (0.30-0.72)

0.33 (0.22-0.62)

0.031

MT-CO3 (mt-cfDNA ) pg/μl^b, median(IQR)

2.38 (1.12-5.22)

2.09 (1.00-5.13)

2.52 (1.48-6.23)

0.571

NE ng/ml , median(IQR)

105.1 (56.5-173.0)

94.0 (47.7-154.0)

115.7 (84.2-212.7)

0.009

LL-37 ng/mL), median(IQR)

39.0 (26.8-55.6)

36.9 (26.5-53.0)

44.3 (31.8-58.0)

0.194

sCD163 ng/mL median(IQR)

647.6 (441.0-951.9)

614.0 (370.0-821.0)

787.0 (560.0-1304.0)

0.002