Table 1 Main clinical and demographic characteristics of the individuals enrolled in the study
From: Blood RNA-Seq profiling reveals a set of circular RNAs differentially expressed in frail individuals
Discovery and validation cohort | Intervention cohort | ||||
|---|---|---|---|---|---|
Robust (N=35) | Frail (N=35) | Pre (N=13) | Post (N=12) | Post + 3m (N=6) | |
Sex | |||||
Female | 20 | 20 | 8 | 8 | 4 |
Male | 15 | 15 | 5 | 4 | 2 |
Age (years) | |||||
Inclusion criteria | >70 years | >70 years | |||
Mean (SD) | 78.8 (±2.63) | 81.0 (±4.96) | 78.2(±3.34) | 78.4(±3.48) | 77.1(±4.27) |
Timed up-and-go (TUG) (seconds) | |||||
Inclusion criteria | <12 s | ≥12 s | |||
Mean (SD) | 8.48 (±0.88) | 15.7 (±3.05) | 10.5(±2.17) | 9.8(±1.41) | 9.8(±1.15) |
Gait Speed (GA) (m/s) | |||||
Inclusion criteria | >0.8 | ≤0.8 | |||
Mean (SD) | 1.13 (±0.12) | 0.64 (±0.10) | - | - | - |
Short Physical Performance Battery (SPPB) (points) | |||||
Inclusion criteria | ≥10 | <10 | |||
Mean (SD) | 11.1 (±0.69) | 7.2 (±1.21) | 7.2 (±1.74) | 8.3 (±1.67) | 7.0 (±1.55) |