Table 1 Subjects’ characteristics
From: Systemic immune response in young and elderly patients after traumatic brain injury
Young control | Young TBI | Elderly control | Elderly TBI | P | |
|---|---|---|---|---|---|
Cohort size, n | 22 | 23 | 21 | 22 | |
Age (year), Median (IQR) | 32 (26–36) | 27 (23–34) | 77 (71–81) | 79 (72–84) | *** |
Sex (male), n (%) | 9 (41) | 14 (61) | 12 (57) | 13 (59) | |
GCS post stabilization, Median (IQR) | 10 (8.5–14) | 9.5 (6.5–14) | |||
Mild TBI (GCS 13–15), n | 12 | 8 | |||
Moderate TBI (GCS 8–12), n | 7 | 7 | |||
Severe TBI (GCS 3–7), n | 4 | 7 | |||
Pupils’ abnormalities, n (%) | 2 (9) | 8 (36) | |||
Subjected to surgery, n (%) | 5 (22) | 9 (41) | |||
Politrauma, n (%) | 8 (35) | 4 (18) | |||
Time to blood specimen collection (h from TBI), Median (IQR) | 20 (14.5–30) | 18 (14–24) | |||
In hospital mortality, n (%) | 0 (0) | 6 (27) | ** | ||
Length of hospitalization (days), Median (IQR) | 11 (4–22) | 13.5 (6–23) | |||
Length of hospitalization for patients who survived to hospital discharge (days), Median (IQR) | 11 (4–22) | 16.5 (11.6–26) | |||
GCS at discharge (survivors), Median (IQR) | 15 (15–15) | 13.5 (11–15) | |||
GOSE at 6 months available on n. of patients | 18/23 | 16/22 | |||
GOSE, Median (IQR) | 7 (5–8) | 2 (1–4) | *** | ||
Favourable outcome (GOSE 5–8) (%) | 18/18 (100) | 2/16 (13) | *** | ||
Unfavourable outcome (GOSE 1–4) (%) | 0/18 (0) | 14/16 (87) | *** |