Table3 T cells and T cell subsets based on thymic scores Flow cytometric data on CD3+ T cells and subsets of CD4+ T cells, regulatory T cells and CD8+ T cells in whole blood are presented based on thymic scores; Score 0, complete fatty replacement, no identifiable soft tissue in the thymic bed, Score 1, predominantly fatty thymus, Score 2, approximately one-half fatty and one-half soft tissue attenuation thymus, and Score 3, predominantly soft tissue attenuation thymus
Thymic scores | |||||
|---|---|---|---|---|---|
0 (n = 615) | 1 (n = 259) | 2 (n = 105) | 3 (n = 69) | pa | |
CD3+ T cells/μL | 1317 (1076–1622) | 1331 (1090–1630) | 1432 (1131–1715) | 1296 (1081–1665) | NS |
CD4+ T cells/μL | 852 (680–1070) | 865 (674–1072) | 882 (729–1166) | 858 (670–1042) | NS |
CD8+ T cells/μL | 401 (287–584) | 438 (314–582) | 450 (332–598) | 419 (376–564) | NS |
CD4+ T cells, % of CD3+ | 67 (58–74) | 67 (59–72) | 66 (60–71) | 65 (58–72) | NS |
CD8+ T cells, % of CD3+ | 32 (25–41) | 32 (26–39) | 32 (27–39) | 34 (27–41) | NS |
Treg cells, % of CD4+ cells | 3.8 (3.2–4.6) | 4.0 (3.3–4.8) | 4.2 (3.4–4.9) | 3.8 (3.3–4.7) | NS |