Table 4 Multiple logistic regression analysis of determinants of complete fatty degeneration of thymus. Independent determinants of complete fatty degeneration of thymus (Score 0) are presented. The group with Score 0 (n = 615) was compared with the following groups; Score 3, predominantly soft tissue (n = 69), Scores ≥ 2, at least one half fatty and one half soft-tissue attenuated thymus (n = 174), or Score ≥ 1, any detectable thymic tissue (n = 433)

Score 0 (n = 615) vs Score 3 (n = 69)

 Age

1.14

1.05–1.24

0.002

 Male sex

3.01

1.26–7.18

 < 0.001

 Abdominal obesity

3.33

1.58–7.01

 < 0.001

 HDL cholesterol

0.43

0.20–0.94

0.034

 Naïve T_reg cells, % of all T_regs

0.97

0.94–0.99

0.021

 Naïve CD8⁺ T cells, % of all CD8⁺

0.95

0.93–0.97

 < 0.001

Score 0 (n = 615) vs Score ≥ 2 (n = 174)

 Age

1.13

1.07–1.20

 < 0.001

 Male sex

3.38

1.95–5.84

 < 0.001

 Abdominal obesity

2.55

1.53–4.27

 < 0.001

 BMI

1.07

1.01–1.14

0.029

 Naïve CD8 + T cells, % of all CD8⁺

0.96

0.95–0.97

 < 0.001

 Dietary intake of fiber

0.97

0.96–0.99

0.022

Score 0 (n = 615) vs Score ≥ 1 (n = 433)

 Age

1.10

1.06–1.14

 < 0.001

 Male sex

2.64

1.84–3.79

 < 0.001

 Abdominal obesity

1.79

1.25–2.56

0.001

 BMI

1.09

1.04–1.14

 < 0.001

 Naïve CD8 + T cells, % of all CD8⁺

0.97

0.96–0.98

 < 0.001

 Dietary intake of fiber

0.98

0.97–0.99

0.027