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Table 5 Multiple linear regression analysis of determinants of CT attenuation and thymic size. Independent determinants of CT attenuation values are presented in subjects with any detectable thymic tissue (Score ≥ 1, n = 433) and thymic size in all subjects (n = 1078)

From: Complete fatty degeneration of thymus associates with male sex, obesity and loss of circulating naïve CD8+ T cells in a Swedish middle-aged population

  

β

P

Adjusted R2

CT attenuationa (HU)

Abdominal obesity

-0.206

 < 0.001

0.16

HDL cholesterol

0.195

0.003

Naïve CD8 + T cells, % of all CD8+

0.165

0.002

Thymic sizeb (AP diameter, mm)

Abdominal obesity

0.150

0.006

0.28

HDL cholesterol

-0.242

 < 0.001

BMI

0.301

 < 0.001

  1. HU Hounsfield units, AP Anteroposterior. β indicates standardized coefficient. Variables included but not retaining statistical significance in the models:
  2. aage, sex, BMI, triglycerides, CRP
  3. bage, triglycerides and CRP
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Immunity & Ageing

ISSN: 1742-4933

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