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Fig. 4 | Immunity & Ageing

Fig. 4

From: B-1 derived anti-Thy-1 B cells in old aged mice develop lymphoma/leukemia with high expression of CD11b and Hamp2 that different from TCL1 transgenic mice

Fig. 4

Microarray mRNA analysis by ATA B lymphoma/leukemia. TC–ZAP70–CD5–, TC–ZAP70+CD5+ vs TC+ZAP70–CD5+ and TC–ZAP70–CD5– vs TC+ZAP70+CD5+. ATA B in spleen. A A1: Higher of TC–ZAP70+CD5+ list. A2,3: higher of TC–ZAP70– than TC+ZAP70–CD5+ (TC– >TC+) and higher TC+ZAP70–CD5+ than TC– (TC+ > TC–) list. A3: add flow cytometry analysis of TC– versus TC+ ATA B lymphoma/leukemia together with WT FO B cell. B B1: TC+ZAP70+CD5+ similar to high TC–ZAP+CD5– cells. B2: TC+ZAP70+CD5+ also several high TC–ZAP70–CD5– cells. TC+>TC– are not listed by genes TC+ZAP70+CD5+ decreased to TC–. B3: TC+ZAP70+CD5+ cells and also TC+ZAP70–CD5+ are not increased to old aged TC– cells (ZAP70–CD5–, ZAP70+CD5+) as TC– > TC+

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