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Fig. 2 | Immunity & Ageing

Fig. 2

From: Role of germinal center and CD39highCD73+ B cells in the age-related tonsillar involution

Fig. 2

Memory B-cells displace BGC with advancing age. (A) Fresh TMC were stained for surface CD20, CD10, CD3, CD44, CD38, CD27 and a dead/live stain as in [8]. Samples were subsequently analyzed by FACS. The gating strategy to identify the different B-cell populations is partially illustrated as in Fig. 1. Percentages and colors designate frequencies of the populations indicated. Bmem= memory B cells, PC = plasma cells (B) Histograms presenting the mean percentage ± SD of the memory B cell population frequencies determined as in A), from 76 individuals, distributed according their age. p value was calculated through unpaired t test, **p < 0.01; **** p < 0.0001

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