Table 1 CAIDE model variables of included participants (n=1,918)
CAIDE model variables | Controls (n =1356) | Cases | ||
|---|---|---|---|---|
All-cause dementia (n =562) | Alzheimer’s disease (n=173) | Vascular dementia (n=199) | ||
Age (years), mean (SD) | 61.7 (6.5) | 66.3 (5.2) | 66.3 (5.1) | 66.5 (5.1) |
Mid-life (50-64 years), n (%) | 867 (63.9) | 207 (36.8) | 65 (37.6) | 68 (34.2) |
Late-life (65-75 years), n (%) | 489 (36.1) | 355 (63.2) | 108 (62.4) | 131 (65.8) |
Education (years), mean (SD) | ||||
≤ 9 | 1036 (76.4) | 448 (79.7) | 141 (81.5) | 160 (80.4) |
> 9 | 320 (23.6) | 114 (20.3) | 32 (18.5) | 39 (19.6) |
Sex, n (%) | ||||
Female | 742 (54.7) | 302 (53.7) | 97 (56.1) | 105 (52.8) |
Male | 614 (45.3) | 260 (46.3) | 76 (43.9) | 94 (47.2) |
SBP (mmHg), mean (SD) | 138.9 (19.1) | 142.2 (19.4) | 142.2 (19.3) | 141.9 (19.8) |
BMI (kg/m2), mean (SD) | 27.8 (4.4) | 27.5 (3.9) | 27.2 (3.7) | 27.6 (3.9) |
Total cholesterol (mmol/L), mean (SD) | 5.9 (1.23) | 5.7 (1.3) | 5.7 (1.3) | 5.7 (1.4) |
Physical activity a, n (%) | ||||
Inactive | 239 (17.6) | 146 (26.0) | 53 (30.6) | 49 (24.6) |
Active | 1117 (82.4) | 416 (74.0) | 120 (69.4) | 150 (75.4) |
APOE genotype, n (%) | ||||
ε4 non-carrier | 1027 (75.7) | 340 (60.5) | 89 (51.5) | 128 (64.3) |
ε4 carrier | 329 (24.3) | 222 (39.5) | 84 (48.5) | 71 (35.68) |