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Table 3 Inflammatory biomarkers selected by LASSO regression in the total cohort (n=1,918)

From: Addition of inflammation-related biomarkers to the CAIDE model for risk prediction of all-cause dementia, Alzheimer’s disease and vascular dementia in a prospective study

Inflammatory  biomarkers

Improvement of the CAIDE models’ predictive ability for dementia outcomes

All-cause dementia

Alzheimer’s disease

Vascular dementia

4E BP1

Model 2

-

-

Beta_NGF

Model 1+2

-

-

CCL23

Model 1+2

-

-

CCL3

Model 2

-

-

CD244

Model 1+2

-

Model 1+2

CST5

-

Model 1+2

-

CXCL1

Model 1+2

-

-

CXCL5

Model 1+2

-

-

EN-RAGE

Model 1+2

Model 1+2

Model 1+2

FGF21

Model 1

-

-

IL18

Model 1+2

-

Model 1+2

IL7

Model 2

Model 2

-

LAP TGF beta1

Model 1+2

Model 1+2

Model 1+2

LIFR

Model 1+2

-

-

MCP3

Model 2

Model 2

-

MMP1

-

Model 2

-

OPG

Model 1+2

-

-

OSM

Model 1+2

-

-

SCF

Model 2

-

-

SIRT2

Model 2

-

-

SLAMF1

Model 1+2

-

-

TNFB

Model 1+2

-

-

TRAIL

-

Model 2

-

VEGFA

Model 1+2

-

-

  1. Model 1 and Model 2 refer to CAIDE Model 1 and CAIDE Model 2, respectively
  2. Abbreviations: For inflammatory biomarker abbreviations, see Supplemental Table 2
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Immunity & Ageing

ISSN: 1742-4933

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