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Table 1 MT-I+II, MT-III, IL-6 mRNAs and zinc content in the thymus from young, old and very old mice.

From: Are zinc-bound metallothionein isoforms (I+II and III) involved in impaired thymulin production and thymic involution during ageing?

Mice MT-I+II (MT-I/βactin) IL-6 (IL-6/βactin) MT-III (MT-III/βactin) Zinc content (μg/gr.) Absolute thymus weight (mg)
Young 0.18 ± 0.02 0.14 ± 0.03 0.48 ± 0.02 62.3 ± 11.2 30.6 ± 5.0
Old 3.52 ± 0.3* 0.23 ± 0.02§ 1.65 ± 0.03* 107.4 ± 27.5** 13.6 ± 2.0§
Very old 1.29 ± 0.6+ 0.18 ± 0.04+ 1.63 ± 0.02* 77.4 ± 8.7 15.4 ± 2.3§
  1. *p < 0.001 when compared to young mice; +p < 0.01 when compared to old mice;
  2. **p < 0.01 when compared to young and very old mice; §p < 0.01 when compared to young mice;
  3. ++p < 0.05 when compared to old mice