Figure 1From: Pinpointing beta adrenergic receptor in ageing pathophysiology: victim or executioner? Evidence from crime scenesClassical pathway of β 2 adrenergic receptor (β 2 AR) activating Gα s protein, which in turn activates the conversion of ATP in cAMP by the adenylate cyclase (AC). An alternative signaling pathway involves Gαi protein. G-protein-linked receptor kinase 2 (GRK2) and β-Arrestin participate in the desensitization process of the receptor.Back to article page