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Table 2 Correlations between cytokine production in H1N1-stimulated PBMC cultures and serum IgG3 levels

From: Effects of age on H1N1-specific serum IgG1 and IgG3 levels evaluated during the 2011–2012 influenza vaccine season

Cytokine in supernatants IgG3 (t7) Person’s r p IgG3 (t28) Person’s r p
TNF-α 0.0861 0.58 0.3545 0.0006
IL-6 0.2264 0.31 0.4556 0.0001
IL-10 0.3120 0.09 0.3963 0.06
IFN-γ 0.1623 0.96 0.1918 0.91
IL-4 0.0215 0.56 0.0467 0.49
IL-5 0.0484 0.43 0.0513 0.40
Blys −0.1604 0.16 −0.1528 0.38
  1. PBMC (106 cells/ml) were isolated from the peripheral blood at t0, thawed and cultured with H1N1 (2 μg), for 3 days. At the end of this time, supernatants were collected and analyzed in ELISA for cytokine production. Correlations were calculated by Pearson’s test, using GraphPad Prism 5 software.