Figure 2
From: Proinflammatory profile of in vitro monocytes in the ageing is affected by lymphocytes presence
Influence of lymphocytes presence on cytokines production. Note that with the presence of lymphocytes the spontaneous production of IL-10 was higher and of TGF-β was lower than that of monocytes, regardless of age. After stimulation with LPS, the presence of lymphocytes resulted in increased IL-6, IL-1β, MCP-1 and IL-10 and decreased CXCL-8 and TGF-β in comparison to pure culture of monocytes from of young patients. With age, the same differences were observed, except for CXCL-8 and TGF-β which production was the same between monocytes and PBMC stimulated with LPS.