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Table 2 Summary of the RCTs using PRP in periodontal surgery

From: Platelet-rich plasma (PRP) in dental and oral surgery: from the wound healing to bone regeneration

Authors Year of publication Number of patients Treatment Follow-up (wks) Main results Effect of PRP
Pradeep et al. 2009 20 Treatment of furcation defects 24 No complete closure of furcation defects weak
Menezes et al. 2012 60 Treatment of infrabony defects 48-192 Positive effect of PRP used with other graft materials in infrabony defects but not when used alone weak
Saini et al. 2011 20 Treatment of infrabony defects 12-24-36 Positive effect of PRP used with other graft materials in infrabony defects moderate
Bharadwaj et al. 2011 10 Treatment of infrabony defects 24 Significant improvement in PD, CAL and bone radio-density strong
Ozdemir et al. 2012 14 Treatment of infrabony defects 24 Positive effect of PRP used with other graft materials in infrabony defects but not when used alone weak
Harnack et al. 2009 22 Treatment of infrabony defects 24 No improvement in PPD and CAL derived from the adjunt of PRP to other graft material weak
Rodrigues et al. 2011   Treatment of infrabony defects 12-24-36 Better clinical results for PRP used with other graft materials in infrabony defects than with PRP used on its own weak
Dori et al. 2008 26 Treatment of infrabony defects 48 No adjunctive benefit with the use of PRP weak
Dori et al. 2009 30 Treatment of infrabony defects 48 No adjunctive benefit with the use of PRP weak
Piemontese et al. 2008 60 Treatment of infrabony defects 48 No adjunctive benefit with the use of PRP weak
Keceli et al. 2008 40 Root coverage 6-36-48 No adjunctive benefit with the use of PRP weak