Table 2 Summary of the RCTs using PRP in periodontal surgery
From: Platelet-rich plasma (PRP) in dental and oral surgery: from the wound healing to bone regeneration
Authors | Year of publication | Number of patients | Treatment | Follow-up (wks) | Main results | Effect of PRP |
|---|---|---|---|---|---|---|
Pradeep et al. | 2009 | 20 | Treatment of furcation defects | 24 | No complete closure of furcation defects | weak |
Menezes et al. | 2012 | 60 | Treatment of infrabony defects | 48-192 | Positive effect of PRP used with other graft materials in infrabony defects but not when used alone | weak |
Saini et al. | 2011 | 20 | Treatment of infrabony defects | 12-24-36 | Positive effect of PRP used with other graft materials in infrabony defects | moderate |
Bharadwaj et al. | 2011 | 10 | Treatment of infrabony defects | 24 | Significant improvement in PD, CAL and bone radio-density | strong |
Ozdemir et al. | 2012 | 14 | Treatment of infrabony defects | 24 | Positive effect of PRP used with other graft materials in infrabony defects but not when used alone | weak |
Harnack et al. | 2009 | 22 | Treatment of infrabony defects | 24 | No improvement in PPD and CAL derived from the adjunt of PRP to other graft material | weak |
Rodrigues et al. | 2011 | Â | Treatment of infrabony defects | 12-24-36 | Better clinical results for PRP used with other graft materials in infrabony defects than with PRP used on its own | weak |
Dori et al. | 2008 | 26 | Treatment of infrabony defects | 48 | No adjunctive benefit with the use of PRP | weak |
Dori et al. | 2009 | 30 | Treatment of infrabony defects | 48 | No adjunctive benefit with the use of PRP | weak |
Piemontese et al. | 2008 | 60 | Treatment of infrabony defects | 48 | No adjunctive benefit with the use of PRP | weak |
Keceli et al. | 2008 | 40 | Root coverage | 6-36-48 | No adjunctive benefit with the use of PRP | weak |