Table 3 Summary of the RCTs, using PRP in soft/bone tissue surgery and implant surgery
From: Platelet-rich plasma (PRP) in dental and oral surgery: from the wound healing to bone regeneration
Authors | Year of publication | Number of patients | Treatment | Follow-up (wks) | Main results | Effect of PRP |
|---|---|---|---|---|---|---|
Anitua et al. | 2006 | 295 | Implantology | 8 | Improvement in implant prognosis | strong |
Anand et al. | 2012 | 11 | Implantology | 12-24-36-48 | Improved early bone apposition around the implant | strong |
Gentile et al. | 2010 | 15 | Reconstructive surgery of the jaw | 2-4-12-24 | Efficacy of PRP treatment in terms of patient satisfaction and low-morbidity | strong |
Wojtowicz et al. | 2007 | 16 | Augmentation of mandibular bone | 12 | PRP is more effective than bone marrow, containing CD34+ cells | strong |
Daif | 2012 | 24 | Bone regeneration of mandibular fractures | 1-12-24 | Direct application of the PRP along the fracture lines may enhance bone regeneration in mandibular fractures | strong |
Khairy et al. | 2012 | 15 | Sinus lift | 12-24 | PRP- enriched bone grafts were associated with superior bone density at 6Â months post grafting | strong |
Poeschl et al. | 2012 | 14 | Sinus lift | 28 | Increased new bone formation when PRP was used | strong |
Cabbar et al. | 2011 | 10 | Sinus lift | 28 | No statistically significant differences were observed | weak |