Table 4 Summary of the case reports using PRP in the BRONJ surgery
From: Platelet-rich plasma (PRP) in dental and oral surgery: from the wound healing to bone regeneration
Authors | Year of publication | Number of patients | Type of lesion | Treatment options | Follow-up (Mths) | Main results | Effect of PRP |
|---|---|---|---|---|---|---|---|
Curi et al. | 2007 | 3 | Jaw lesions | Â | 6-8 | Resolution of all lesions | strong |
Lee et al. | 2007 | 2 | Complications of dental implants: oral sinus communication and lesion on the jaw ramus | Closure of the oroantral communication by rotating a large palatally-based pedicle flap over the defect; surgical debridment of the lesion of the ramus | 6-9 | Resolution of pain and complete closure of exposed bone | strong |
Adornato et al. | 2007 | 12 | Soft tissue ulcerations and bone exposure | Marginal resection limited to the alveolar bone | 6 | Ten patients showed complete soft tissue healing | strong |
Cetiner et al. | 2009 | 1 | Exposed necrotic bone in the alveolus | Marginal resection of the mandibular necrotic bone | 6 | Complete healing of the oral mucosa and alveolar bone at the surgical site | strong |
Bocanegra et al. | 2012 | 8 | Exposed necrotic bone in the mandibula and maxilla | Removal of necrotic bone and curettage of the underlying bone | 14 | Fast mucosal healing, reduced need for analgesics and resolution of mouth lesions, without evidence of exposed bone. | strong |
Mozzati et al. | 2012 | 32 | Jaw lesions | Resection of the necrotic bone | Â | The orthopanoramic X-ray and computed tomography performed before and after surgery showed successful outcomes | strong |
Coviello et al. | 2012 | 7 | Jaw lesions | Surgical debridement and sequestrectomy | 3 | Improvement in wound healing and reduction of bone exposure | strong |