Figure 1From: Increased activation and cytokine secretion in B cells stimulated with leptin in aged humansEffect of leptin on activation of B cells and B cell subsets. Purified B cells from young and aged subjects were stimulated with leptin (50 ng/ml) for 24 hours and expression of CD25 and CD69 as activation markers, using specific antibodies and isotype controls. Blue lines are for unactivated B cells, and red line for leptin-activated B cells.Back to article page