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Table 1 Effect of Leptin on the expression of activation markers on B cell subsets (%)

From: Increased activation and cytokine secretion in B cells stimulated with leptin in aged humans

Marker

Young

Aged

 

CD19

CD5+

CD5-

CD19

CD5+

CD5-

CD25

Control

2.8 ± 0.4

3.5 ± 0.4

3.0 ± 0.3

3.5 ± 0.2

5.0 ± 0.7

1.8 ± 0.4

Activated

8.3 ± 1.1

4.0 ± −.3

10.0 ± 1.3

26.3 ± 2.8

15.0 ± 2.3

12.0 ± 1.9

CD69

Control

1.8 ± 0.2

2.4 ± 0.5

1.9 ± 0.5

5.5 ± 1.0

3.1 ± 0.4

2.5 ± 0.3

Activated

4.3 ± 0.6

2.6 ± 0.3

4.8 ± 0.3

8.2 ± 0.5

7.6 ± 0.8

6.9 ± 0.4

  1. P value:
  2. CD25, Aging vs. Young: CD19 = P < 0.01, CD5 + = P < 0.001, CD5- = P < 0.05.
  3. CD69, Aging vs. Young: CD19 = P < 0.05, CD5+ = P < 0.01, CD5- = P < 0.05.