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Table 1 Effect of Leptin on the expression of activation markers on B cell subsets (%)

From: Increased activation and cytokine secretion in B cells stimulated with leptin in aged humans

Marker Young Aged
  CD19 CD5+ CD5- CD19 CD5+ CD5-
CD25 Control 2.8 ± 0.4 3.5 ± 0.4 3.0 ± 0.3 3.5 ± 0.2 5.0 ± 0.7 1.8 ± 0.4
Activated 8.3 ± 1.1 4.0 ± −.3 10.0 ± 1.3 26.3 ± 2.8 15.0 ± 2.3 12.0 ± 1.9
CD69 Control 1.8 ± 0.2 2.4 ± 0.5 1.9 ± 0.5 5.5 ± 1.0 3.1 ± 0.4 2.5 ± 0.3
Activated 4.3 ± 0.6 2.6 ± 0.3 4.8 ± 0.3 8.2 ± 0.5 7.6 ± 0.8 6.9 ± 0.4
  1. P value:
  2. CD25, Aging vs. Young: CD19 = P < 0.01, CD5 + = P < 0.001, CD5- = P < 0.05.
  3. CD69, Aging vs. Young: CD19 = P < 0.05, CD5+ = P < 0.01, CD5- = P < 0.05.