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Table 2 Effect of Leptin on the expression of activation markers on B cell subsets (MFI)

From: Increased activation and cytokine secretion in B cells stimulated with leptin in aged humans

Marker Young Aged
   CD19 CD5+ CD5- CD19 CD5+ CD5-
CD25 Control 3.6 ± .4 5.6 ± 2 5.6 ± 2 10 ± 4 7 ± 1.25 10 ± 7
Activated 9.6 ± 1.7 9.5 ± 1.4 9.5 ± 1.4 26 ± 2 15 ± 2.5 51 ± 4.6
CD69 Control 4.5 ± 2 8.8 ± 5 4.1 ± 1.6 4.5 ± .4 7 ± 3.5 3.6 ± 8
Activated 7.6 ± 2.6 11 ± 5.9 7.3 ± 1.7 8.6 ± .47 20 ± 5.7 8 ± .8
  1. P value:
  2. CD25, Aging vs. Young: CD19 = P < 0.01, CD5 + = P < 0.001, CD5- = P < 0.045.
  3. CD69, Aging vs. Young: CD19 = ns, CD5+ = P < 0.02, CD5- = ns.