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Table 2 Delayed-type hypersensitivity in the 3 populations

From: Does aging affect the immune status? A comparative analysis in 300 healthy volunteers from France, Austria and Spain

 

France

Austria

Spain

ANOVA

(n = 99)

(n = 101)

(n = 100)

Number of positive reactions

3.4 ± 0.2 a

6.9 ± 0.1 b

1.1 ± 0.1 c

<0.0001

Cumulative score (mm)

17.7 ± 0.9 a

22.7 ± 1.2 b

7.1 ± 0.8 c

<0.0001

Proteus mirabilis

2.4 ± 0.2a

3.2 ± 0.2b

0.6 ± 0.2c

<0.0001

Trichophyton

0.9 ± 0.1a

1.4 ± 0.2b

0.2 ± 0.1c

<0.0001

Candida albicans

2.3 ± 0.2a

2.7 ± 0.3a

0.4 ± 0.1b

<0.0001

Tetanus

4.2 ± 0.3a

6.4 ± 0.4b

2.5 ± 0.3c

<0.0001

Diphteria

1.5 ± 0.2a

2.8 ± 0.4b

0.6 ± 0.2c

<0.0001

Streptococcus

0.9 ± 0.2a

1.3 ± 0.2b

0.2 ± 0.1c

<0.0001

Tuberculin

5.4 ± 0.3a

4.5 ± 0.5b

2.7 ± 0.4c

<0.0001

  1. Mean ± SEM.
  2. Two-way ANOVA was performed to discriminate among the two factors age-group, country and their interactions followed by a post-hoc Newman-Keuls test. A significant country-related effect was observed independently of the age-group: a≠b≠c, p < 0.0001.