Table 4 ACT, HMC-CR, INF-γ, IL-1β, IL-6 genotype /allele frequencies in patients with chronic periodontitis and CTR
From: Variations in inflammatory genes are associated with periodontitis
ACT | GG* | GT | TT | G carr | T carr |
|---|---|---|---|---|---|
Periodontitis | (18) | (26) | (11) | (44) | (37) |
(n = 55) | 32.7 | 47.3 | 20 | 80.0 | 67.3 |
CTR | (108) | (222) | (122) | (330) | (344) |
(n = 452) | 23.9 | 49.1 | 27.0 | 73 | 76.1 |
X2 = 2.487 p = 0.288 | |||||
X2 = 1.238 p = 0.266 Allele G | |||||
X2 = 2.049 p = 0.152 Allele T | |||||
* wild type genotype | |||||
HMG-CR | CC* | CA | AA | C carr | A carr |
periodontitis | (56) | (8) | (2) | (64) | (10) |
84.8 | 12.1 | 3 | 97 | 15.2 | |
(n = 66) | |||||
CTR | (349) | (63) | (7) | (412) | (70) |
(n = 419) | 83.3 | 15 | 1.7 | 98.3 | 16.7 |
X2 = 0.915 p = 0.633 | |||||
X2 = 0.579 p = 0.447 Allele C | |||||
X2 = 0.100 p = 0.752 Allele A | |||||
* wild type genotype | |||||
IL-1β | CC* | CT | TT | C carr | T carr |
periodontitis | (34) | (29) | (8) | (63) | (37) |
(n = 71) | 47.9 | 40.8 | 11.3 | 88.7 | 52.1 |
CTR | (142) | (129) | (35) | (271) | (166) |
(n = 306) | 46.4 | 42.2 | 11.4 | 88.6 | 54.2 |
X2 = 0.052 p = 0.974 | |||||
X2 = 0.002 p = 0.968 Allele C | |||||
X2 = 0.106 p = 0.745 Allele T | |||||
* wild type genotype | |||||
INF-γ | TT* | TA | AA | T carr | A carr |
periodontitis | (16) | (38) | (14) | (53) | (52) |
(n = 68) | 23.5 | 55.9 | 20.6 | 79.1 | 77.6 |
CTR | (73) | (102) | (67) | (174) | (170) |
(n = 242) | 30.2 | 42.1 | 27.7 | 71.9 | 70.2 |
X2 = 4.055 p = 0.132 | |||||
X2 = 1.397 p = 0.237 Allele T | |||||
X2 = 1.407 p = 0.236 Allele A | |||||
* wild type genotype | |||||
IL-6 | GG* | GC | CC | G carr | C carr |
periodontitis | (40) | (25) | (12) | (64) | (36) |
(n = 77) | 51.9 | 32.5 | 15.6 | 84.2 | 47.4 |
CTR | (119) | (125) | (34) | (244) | (159) |
57.2 | |||||
(n = 278) | 42.8 | 45 | 12.2 | 87.8 | |
X2 = 2.329 p = 0.127 | |||||
X2 = 0.669 p = 0.413 Allele G; X2 = 2.666 p = 0.103 Allele C | |||||
* wild type genotype | |||||