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Table 1 TLR-6 genotype distribution in CAD patients and controls

From: Association of a common TLR-6 polymorphism with coronary artery disease – implications for healthy ageing?

 

N

Variant allele (%)

P-value

Genotype (%)

Odds ratio (95% CI)

 

Pro/pro

Pro/ser

Ser/ser

 
 

P-value

  

ser

 

C/C

C/T

T/T

 

Study group

       

Controls 1

300

278 (46.3)

0.008

87 (29.0)

148 (49.3)

65 (21.7)

0.64

Patients

207

157 (37.9)

81 (39.1)

95 (45.9)

31 (15.0)

0.38-1.02

0.06

Confirmatory group

       

Controls 2

305

268 (43.9)

0.23

97 (31.8)

148 (48.5)

60 (19.7)

0.76

Patients

306

248 (40.5)

106 (34.6)

152 (49.7)

48 (15.7)

0.50-1.15

0.20

Combined

       

Controls

605

546 (45.1)

0.007

184 (30.4)

296 (48.9)

125 (20.7)

0.69

Patients

513

405 (39.5)

 

187 (36.5)

247 (48.1)

79 (15.4)

0.513-0.953

 

0.02

  1. P-values were determined by chi2 test. The odds ratios were determined by comparing the homozygous genotype with the wild type and the heterozygous genotype.