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Table 1 Genotype distribution and allele frequency of the A-2518G MCP-1 promoter polymorphism in patients with probable AD, patients with MCI and controls (CTR) from Northern Italy

From: Monocyte chemoattractant protein-1 promoter polymorphism and plasma levels in alzheimer’s disease

 

AA

AG

GG

Allele A

Allele G

 

(n) %

(n) %

(n) %

(n) %

(n) %

AD (n=291)

(139) 47.8

(130) 44.7

(22) 7.6

(269) 92.4

(152) 52.2

MCI(n=88)

(49) 55.7

(37) 42.0

(2) 2.3

(86) 97.7

(38) 43.2

CTR(n=146)

(69) 47.3

(66) 45.2

(11) 7.5

(135) 92.5

(77) 52.7

  1. Statistics.
  2. AD vs CTR (genotypic distribution): Pearson χ2= 0.11, p=0.994;
  3. logistic regression adjusted for age and APOE e4 p=0.713 c.i 95% (0.981-1.013).
  4. CTR vs MCI (genotypic distribution): Pearson χ2= 3.633, p=0.163;
  5. logistic regression adjusted for age and APOE e4 p=0.988 c.i 95% (0.970-1.007).
  6. AD vs MCI (genotypic distribution): Pearson χ2= 3.942, p=0.139;
  7. logistic regression adjusted for age and APOE e4 p=0.299 c.i 95% (0.994-1.018).
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Immunity & Ageing

ISSN: 1742-4933

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