Figure 9

The effect of three weeks ex vivo supplementation with 30 μM ebselen or 7.5 mM NAC on the levels of oxidative DNA damage in human PBMCs or CD4⁺T cells ex vivo isolated from fresh human blood derived from five different healthy donors aged 25–30 years. A &B denote the impact of 30 μM ebselen and C &D denote the impact of 7.5 mM NAC. The bars indicate the mean ± S.D. Values statistically different from their controls (Student’s t-test, 95% confidence level) are indicated with an asterisk. ** p < 0.01, *** p < 0.001 - Significantly higher than the levels of DNA damage in non-supplemented cells.