Figure 3
Mast cells and the liver cell interactions. The parenchyma of the liver is a complex structure with different cell types having various functions in normal liver function and disease response. These include: macrophages, or Kupffer cells, hepatic stellate cells, sinusoidal endothelial cells, vascular endothelial cells, fibroblasts and pit cells. It has been ascertained that all these cells (in addition to biliary cells) play definitive roles in liver pathophysiology and determine complex interactions with hepatic MCs.