Figure 2

Redistribution of CD11c⁺DC subsets in elderly-derived mesLNs and livers. CD4⁺CD8α^-, CD4^-CD8α⁺, CD4^-CD8α^- DCs (A) and B220⁺GR1⁺ pDCs (B) were identified within gated CD11c⁺ cells. DC subset distribution is shown as a percentage of the CD11c⁺ cells in mesLN (C) and liver (D); data is shown as individual values and mean ± SEM. * = p ≤ 0.05; ** = p ≤ 0.01; *** = p ≤ 0.001; **** = p ≤ 0.0001. The distribution of CD11c⁺ DC subsets in the remaining tissues are shown as mean percentages of CD11c⁺ cells (E). Data in (C), (D) and (E) are pooled from 2 separate experiments, total n = 7 – 8 mice/group.