Figure 12

Double biomarkers of homeostasis to evaluate the ability of our physiological system to control the inflammation and preserve the state of health: "Evaluation System". The double biomarkers are of: 1) a type if the levels of Trx1—sCD30 molecules in both gender are within the normal physiological ranges and the levels of IFNy—IL10, IL6—IL4 and IFNy—IL4 for men are in the physiological ranges and they are related by a direct proportionality: their amounts may be equal, above or under the mean and they both increase or decrease in the same sense, positive or negative; the levels of IL6—IFNy and IL6—IL10 for women are in the physiological ranges, and they are respectively related by direct and inverse proportionality: their quantities are equal, above or under the mean, they both increase or decrease with the same verse, positive or negative, in case of direct proportionality, and in inverse verse, positive the first and negative the second or vice versa, in case of inverse proportionality; 2) b type if the levels of Trx1—sCD30 molecules in both gender are or are not in the normal physiological ranges and the levels of IFNy—IL10, IL6—IL4 and IFNy—L4 in men are not in the physiologic ranges, but they are still related by the same direct proportionality, corresponding to the homeostatic condition; the levels of IL6—IL10 and IL6—FNy in women are not in the physiological ranges, but they are still related by the same proportionalities, inverse and direct, corresponding to the homeostatic condition; 3) c type if levels of Trx1—sCD30 molecules in both gender are not in the normal physiological ranges and the levels of IFNy—IL10, IL6—IL4 and IFNy—IL4 in men are not in the physiological ranges and they are not related with the same direct proportionality of the homeostatic state, but they are characterized by an inverse proportionality; the levels of IL6—IFNy and IL6—IL10 in women are not in the physiological ranges and they are not related by the same inverse and direct proportionality of the homeostatic state, but the first couple by an inverse proportionality and the second by a direct one.