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Figure 6 | Immunity & Ageing

Figure 6

From: Severe acute respiratory syndrome-coronavirus infection in aged nonhuman primates is associated with modulated pulmonary and systemic immune responses

Figure 6

Comparison of T lymphocyte responses to SARS-CoV infection in the aged and juvenile monkey. CD8 T cells were evaluated by flow cytometric analysis for coexpression of naïve cell markers CD45RA and CCR7 (A-C); proliferation marker, Ki67 (D-F); and cytotoxic enzyme, granzyme B (G-I) in the peripheral blood, lung and tracheobronchial lymph nodes. Graphs represent average values (+/−SE). The gating strategy for flow cytometric analysis is shown in Additional file 1: Figures S1 and Additional file 2: Figure S2. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 in unpaired student T-tests comparing age groups.

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