From: Air pollution and subclinical airway inflammation in the SALIA cohort study
Total area | Rural area | Urban area | p-Valueb | ||||
---|---|---|---|---|---|---|---|
Geometric mean (gsd)a | N | Geometric mean (gsd)a | N | Geometric mean (gsd)a | N | ||
Markers in exhaled breath condensate | |||||||
pH | 7.1 (1.1) | 381 | 7.1 (1.1) | 185 | 7.1 (1.1) | 196 | 0.854 |
NO derivatives [μM] | 6.3 (1.8) | 384 | 6.0 (1.8) | 186 | 6.6 (1.9) | 198 | 0.1379 |
LTB4 [pg/ml]e | 8.9 (1.4) | 372 | 8.7 (1.4) | 181 | 9.0 (1.4) | 191 | 0.2522 |
8-iso-PGF 2 α [pg/ml] | 111 (1.9) | 363 | 112 (1.9) | 175 | 110 (2.0) | 188 | 0.8583 |
Soluble markers in induced sputum | |||||||
Total protein content [μg/ml] | 207 (2.1) | 324 | 196 (2.1) | 160 | 219 (2.0) | 164 | 0.1687 |
IL-8 [pg/ml]c | 974 (3.1) | 318 | 991 (3.2) | 158 | 959 (3.0) | 160 | 0.7991 |
NO derivatives [μM] | 14.0 (2.2) | 324 | 12.5 (1.9) | 160 | 15.8 (2.4) | 164 | 0.0072 |
IL-1β [pg/ml] | 15.1 (2.9) | 320 | 15.8 (3.1) | 159 | 14.5 (2.7) | 161 | 0.5007 |
TNF-α [pg/ml] | 1.8 (2.0) | 320 | 1.6 (2.0) | 158 | 2.0 (2.0) | 162 | 0.0067 |
LTB4 [pg/ml] | 642 (2.2) | 324 | 608 (2.1) | 160 | 679 (2.2) | 164 | 0.1988 |
MMP-9 [ng/ml]d | 94.0 (4.5) | 279 | 84.0 (4.9) | 135 | 104 (4.2) | 144 | 0.2431 |
Cells in induced sputum | |||||||
Total number of cells (x105) | 14.5 (2.7) | 324 | 13.0 (2.7) | 160 | 16.2 (2.6) | 164 | 0.0433 |
Macrophagese | 0.1 (19.2) | 321 | 0.1 (18.3) | 158 | 0.1 (20.3) | 163 | 0.4582 |
Neutrophils (x104)f | 15.6 (6.2) | 321 | 12.2 (6.4) | 158 | 19.8 (5.9) | 163 | 0.0175 |
Eosinophilse | 0.03 (9.1) | 321 | 0.03 (8.0) | 158 | 0.04 (10.1) | 163 | 0.3601 |