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Table 3 Distribution of inflammatory markers of study population in rural and in urban areas in 2008/2009

From: Air pollution and subclinical airway inflammation in the SALIA cohort study

 

Total area

Rural area

Urban area

p-Valueb

 

Geometric mean (gsd)a

N

Geometric mean (gsd)a

N

Geometric mean (gsd)a

N

 

Markers in exhaled breath condensate

       

pH

7.1 (1.1)

381

7.1 (1.1)

185

7.1 (1.1)

196

0.854

NO derivatives [μM]

6.3 (1.8)

384

6.0 (1.8)

186

6.6 (1.9)

198

0.1379

LTB4 [pg/ml]e

8.9 (1.4)

372

8.7 (1.4)

181

9.0 (1.4)

191

0.2522

8-iso-PGF 2 α [pg/ml]

111 (1.9)

363

112 (1.9)

175

110 (2.0)

188

0.8583

Soluble markers in induced sputum

       

Total protein content [μg/ml]

207 (2.1)

324

196 (2.1)

160

219 (2.0)

164

0.1687

IL-8 [pg/ml]c

974 (3.1)

318

991 (3.2)

158

959 (3.0)

160

0.7991

NO derivatives [μM]

14.0 (2.2)

324

12.5 (1.9)

160

15.8 (2.4)

164

0.0072

IL-1β [pg/ml]

15.1 (2.9)

320

15.8 (3.1)

159

14.5 (2.7)

161

0.5007

TNF-α [pg/ml]

1.8 (2.0)

320

1.6 (2.0)

158

2.0 (2.0)

162

0.0067

LTB4 [pg/ml]

642 (2.2)

324

608 (2.1)

160

679 (2.2)

164

0.1988

MMP-9 [ng/ml]d

94.0 (4.5)

279

84.0 (4.9)

135

104 (4.2)

144

0.2431

Cells in induced sputum

       

Total number of cells (x105)

14.5 (2.7)

324

13.0 (2.7)

160

16.2 (2.6)

164

0.0433

Macrophagese

0.1 (19.2)

321

0.1 (18.3)

158

0.1 (20.3)

163

0.4582

Neutrophils (x104)f

15.6 (6.2)

321

12.2 (6.4)

158

19.8 (5.9)

163

0.0175

Eosinophilse

0.03 (9.1)

321

0.03 (8.0)

158

0.04 (10.1)

163

0.3601

  1. aGeometric standard deviation, bp-Value of t-test for the difference of geometric means between rural and urban area, cValues > 20000 set to 20000, dValues <2 set to 2, eTransformed to binary variables because for LTB4 in EBC 83.3% of the values were below the detection limit and for macrophages 56% and for eosinophils 77% of the values were equal to zero, fValues > 5x106 set to 5x106; Values < 1 set to 1 for the log-transformation.