TY - JOUR AU - Medzhitov, R. AU - Janeway, C. PY - 2000 DA - 2000// TI - Innate immunity JO - N Engl J Med VL - 343 UR - https://doi.org/10.1056/NEJM200008033430506 DO - 10.1056/NEJM200008033430506 ID - Medzhitov2000 ER - TY - JOUR AU - Janeway, C. AU - Medzhitov, R. PY - 2002 DA - 2002// TI - Viral interference with IL-1 and toll signaling JO - Annu Rev Immunol VL - 20 UR - https://doi.org/10.1146/annurev.immunol.20.083001.084359 DO - 10.1146/annurev.immunol.20.083001.084359 ID - Janeway2002 ER - TY - JOUR AU - Krieger, M. PY - 1997 DA - 1997// TI - The other side of scavenger receptors: pattern recognition for host defense JO - Curr Opin Lipidol VL - 8 UR - https://doi.org/10.1097/00041433-199710000-00006 DO - 10.1097/00041433-199710000-00006 ID - Krieger1997 ER - TY - JOUR AU - Muzio, M. AU - Natoli, G. AU - Saccani, S. AU - Levrero, M. AU - Mantovani, A. PY - 1998 DA - 1998// TI - The human toll signaling pathway: divergence of nuclear factor kappaB and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6) JO - J Exp Med VL - 187 UR - https://doi.org/10.1084/jem.187.12.2097 DO - 10.1084/jem.187.12.2097 ID - Muzio1998 ER - TY - JOUR AU - Guha, M. AU - Mackman, N. PY - 2001 DA - 2001// TI - LPS induction of gene expression in human monocytes JO - Cell Signal VL - 13 UR - https://doi.org/10.1016/S0898-6568(00)00149-2 DO - 10.1016/S0898-6568(00)00149-2 ID - Guha2001 ER - TY - CHAP AU - Mitchell, R. N. AU - Cotran, R. S. PY - 2003 DA - 2003// TI - Acute and Chronic Inflammation BT - Robbins Basic Pathology PB - Saunderrs CY - Philadelphia, USA ID - Mitchell2003 ER - TY - STD TI - Lio D, Caruso C: IL-10, Genetic Polymorphism and Its Relevance to Age-related Diseases. Interleukin-10. Edited by: Francesco M Marincola. © 2004 Eurekah.com ID - ref7 ER - TY - JOUR AU - Bidwell, J. AU - Keen, L. AU - Gallagher, G. AU - Kimberly, R. AU - Huizinga, T. AU - McDermott, M. F. AU - Oksenberg, J. AU - McNicholl, J. AU - Pociot, F. AU - Hardt, C. AU - D'Alfonso, S. PY - 1999 DA - 1999// TI - Cytokine gene polymorphism in human disease: on-line databases JO - Genes Immun VL - 1 UR - https://doi.org/10.1038/sj.gene.6363645 DO - 10.1038/sj.gene.6363645 ID - Bidwell1999 ER - TY - JOUR AU - Gabay, C. AU - Kushner, I. PY - 1999 DA - 1999// TI - Acute-phase proteins and other systemic responses to inflammation JO - N Engl J Med VL - 340 UR - https://doi.org/10.1056/NEJM199902113400607 DO - 10.1056/NEJM199902113400607 ID - Gabay1999 ER - TY - JOUR AU - Pepys, M. B. AU - Hirschfield, G. M. PY - 2003 DA - 2003// TI - C-reactive protein: a critical update JO - J Clin Invest VL - 111 UR - https://doi.org/10.1172/JCI200318921 DO - 10.1172/JCI200318921 ID - Pepys2003 ER - TY - JOUR AU - Candore, G. AU - Colonna-Romano, G. AU - Lio, D. AU - Caruso, C. PY - 2003 DA - 2003// TI - Immunological and Immunogenetic markers of successful and unsuccessful ageing JO - Advances in Cell Aging and Gerontology VL - 13 UR - https://doi.org/10.1016/S1566-3124(02)13003-3 DO - 10.1016/S1566-3124(02)13003-3 ID - Candore2003 ER - TY - JOUR AU - Pawelec, G. AU - Ouyang, Q. AU - Colonna-Romano, G. AU - Candore, G. AU - Lio, D. AU - Caruso, C. PY - 2002 DA - 2002// TI - Is human immunosenescence clinically relevant? Looking for 'immunological risk phenotypes' JO - Trends Immunol VL - 23 UR - https://doi.org/10.1016/S1471-4906(02)02255-X DO - 10.1016/S1471-4906(02)02255-X ID - Pawelec2002 ER - TY - JOUR AU - Pawelec, G. AU - Akbar, A. AU - Caruso, C. AU - Effros, R. AU - Grübeck-Loebenstein, B. AU - Wikby, A. PY - 2004 DA - 2004// TI - Is immunosenescence infectious? Contribution of persistent Herpes viruses to immunosenescence and influence on human longevity JO - Trends Immunol VL - 25 UR - https://doi.org/10.1016/j.it.2004.05.006 DO - 10.1016/j.it.2004.05.006 ID - Pawelec2004 ER - TY - JOUR AU - Lloberas, J. AU - Celada, A. PY - 2002 DA - 2002// TI - Effect of aging on macrophage function JO - Exp Geront VL - 37 UR - https://doi.org/10.1016/S0531-5565(02)00125-0 DO - 10.1016/S0531-5565(02)00125-0 ID - Lloberas2002 ER - TY - JOUR AU - Renshaw, M. AU - Rockwell, J. AU - Engleman, C. AU - Gewirtz, A. AU - Katz, J. AU - Sambhara, S. PY - 2002 DA - 2002// TI - Cutting edge: impaired Toll-like receptor expression and function in aging JO - J Immunol VL - 169 UR - https://doi.org/10.4049/jimmunol.169.9.4697 DO - 10.4049/jimmunol.169.9.4697 ID - Renshaw2002 ER - TY - JOUR AU - Pawelec, G. AU - Solana, R. AU - Remarque, E. AU - Mariani, E. PY - 1998 DA - 1998// TI - Impact of aging on innate immunity JO - J Leukoc Biol VL - 64 ID - Pawelec1998 ER - TY - JOUR AU - Plackett, T. P. AU - Boehmer, E. D. AU - Faunce, D. E. AU - Kovacs, E. J. PY - 2004 DA - 2004// TI - Aging and innate immune cells JO - J Lekoc Biol VL - 76 UR - https://doi.org/10.1189/jlb.1103529 DO - 10.1189/jlb.1103529 ID - Plackett2004 ER - TY - JOUR AU - Di Lorenzo, G. AU - Balistreri, C. R. AU - Candore, G. AU - Cigna, D. AU - Colombo, A. AU - Romano, G. C. AU - Colucci, A. T. AU - Gervasi, F. AU - Listi, F. AU - Potestio, M. AU - Caruso, C. PY - 1999 DA - 1999// TI - Granulocyte and natural killer activity in the elderly JO - Mech Ageing Dev VL - 108 UR - https://doi.org/10.1016/S0047-6374(98)00156-0 DO - 10.1016/S0047-6374(98)00156-0 ID - Di Lorenzo1999 ER - TY - JOUR AU - Fagiolo, U. AU - Cossarizza, A. AU - Scala, E. AU - Fanales-Belasio, E. AU - Ortolani, C. AU - Cozzi, E. AU - Monti, D. AU - Franceschi, C. AU - Paganelli, R. PY - 1993 DA - 1993// TI - Increased cytokine production in mononuclear cells of healthy elderly people JO - Eur J Immunol VL - 23 UR - https://doi.org/10.1002/eji.1830230950 DO - 10.1002/eji.1830230950 ID - Fagiolo1993 ER - TY - JOUR AU - Bruunsgaard, H. AU - Pedersen, M. AU - Pedersen, B. K. PY - 2001 DA - 2001// TI - Aging and proinflammatory cytokines JO - Curr Opin Hematol VL - 131 UR - https://doi.org/10.1097/00062752-200105000-00001 DO - 10.1097/00062752-200105000-00001 ID - Bruunsgaard2001 ER - TY - JOUR AU - Ershler, W. B. AU - Keller, E. T. PY - 2000 DA - 2000// TI - Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty JO - Annu Rev Med VL - 51 UR - https://doi.org/10.1146/annurev.med.51.1.245 DO - 10.1146/annurev.med.51.1.245 ID - Ershler2000 ER - TY - JOUR AU - Baggio, G. AU - Donazzan, S. AU - Monti, D. AU - Mari, D. AU - Martini, S. AU - Gabelli, C. AU - Dalla Vestra, M. AU - Previato, L. AU - Guido, M. AU - Pigozzo, S. AU - Cortella, I. AU - Crepaldi, G. AU - Franceschi, C. PY - 1998 DA - 1998// TI - Lipoprotein(a) and lipoprotein profile in healthy centenarians: a reappraisal of vascular risk factors JO - FASEB J VL - 12 ID - Baggio1998 ER - TY - JOUR AU - Dumont, P. AU - Balbeur, L. AU - Remacle, J. AU - Toussaint, O. PY - 2000 DA - 2000// TI - Appearance of biomarkers of in vitro ageing after successive stimulation of WI-38 fibroblasts with IL-1alpha and TNF-alpha: senescence associated beta-galactosidase activity and morphotype transition JO - J Anat VL - 197 UR - https://doi.org/10.1046/j.1469-7580.2000.19740529.x DO - 10.1046/j.1469-7580.2000.19740529.x ID - Dumont2000 ER - TY - JOUR AU - Vasto, S. AU - Caruso, C. PY - 2005 DA - 2005// TI - Immunity & Ageing: a new journal looking at ageing from an immunological point of view JO - Immun Ageing VL - 2 UR - https://doi.org/10.1186/1742-4933-2-1 DO - 10.1186/1742-4933-2-1 ID - Vasto2005 ER - TY - JOUR AU - Pawelec, G. AU - Barnett, Y. AU - Forsey, R. AU - Frasca, D. AU - Globerson, A. AU - McLeod, J. AU - Caruso, C. AU - Franceschi, C. AU - Fulop, T. AU - Gupta, S. AU - Mariani, E. AU - Mocchegiani, E. AU - Solana, R. PY - 2002 DA - 2002// TI - T cells and aging JO - Front Biosci VL - 7 ID - Pawelec2002 ER - TY - JOUR AU - Franceschi, C. AU - Bonafe, M. AU - Valensin, S. AU - Olivieri, F. AU - De Luca, M. AU - Ottaviani, E. AU - De Benedictis, G. PY - 2000 DA - 2000// TI - Inflamm-aging. An evolutionary perspective on immunosenescence JO - Ann N Y Acad Sci VL - 908 ID - Franceschi2000 ER - TY - JOUR AU - Franceschi, C. AU - Bonafe, M. PY - 2003 DA - 2003// TI - Centenarians as a model for healthy aging JO - Biochem Soc Trans VL - 31 UR - https://doi.org/10.1042/bst0310457 DO - 10.1042/bst0310457 ID - Franceschi2003 ER - TY - JOUR AU - Krabbe, K. S. AU - Pedersen, M. AU - Bruunsgaard, H. PY - 2004 DA - 2004// TI - Inflammatory mediators in the elderly JO - Exp Gerontol VL - 39 UR - https://doi.org/10.1016/j.exger.2004.01.009 DO - 10.1016/j.exger.2004.01.009 ID - Krabbe2004 ER - TY - JOUR AU - Rudin, E. AU - Barzilai, N. PY - 2005 DA - 2005// TI - Inflammatory peptides derived from adipose tissue JO - Immun Ageing VL - 2 UR - https://doi.org/10.1186/1742-4933-2-1 DO - 10.1186/1742-4933-2-1 ID - Rudin2005 ER - TY - JOUR AU - Finch, C. E. AU - Crimmins, E. M. PY - 2004 DA - 2004// TI - Inflammatory exposure and historical changes in human life-spans JO - Science VL - 305 UR - https://doi.org/10.1126/science.1092556 DO - 10.1126/science.1092556 ID - Finch2004 ER - TY - JOUR AU - Ridker, P. M. AU - Morrow, D. A. PY - 2003 DA - 2003// TI - C-reactive protein, inflammation, and coronary risk JO - Cardiol Clin VL - 21 UR - https://doi.org/10.1016/S0733-8651(03)00079-1 DO - 10.1016/S0733-8651(03)00079-1 ID - Ridker2003 ER - TY - JOUR AU - Zhu, J. AU - Quyyumi, A. A. AU - Norman, J. E. AU - Csako, G. AU - Waclawiw, M. A. AU - Shearer, G. M. AU - Epstein, S. E. PY - 2000 DA - 2000// TI - Effects of total pathogen burden on coronary artery disease risk and C-reactive protein levels JO - Am J Cardiol VL - 85 UR - https://doi.org/10.1016/S0002-9149(99)00653-0 DO - 10.1016/S0002-9149(99)00653-0 ID - Zhu2000 ER - TY - JOUR AU - Ferrucci, L. AU - Harris, T. B. AU - Guralnik, J. M. AU - Tracy, R. P. AU - Corti, M. C. AU - Cohen, H. J. AU - Penninx, B. AU - Pahor, M. AU - Wallace, R. AU - Havlik, R. J. PY - 1999 DA - 1999// TI - Serum IL-6 level and the development of disability in older persons JO - J Am Geriatr Soc VL - 47 UR - https://doi.org/10.1111/j.1532-5415.1999.tb01583.x DO - 10.1111/j.1532-5415.1999.tb01583.x ID - Ferrucci1999 ER - TY - JOUR AU - Harris, T. B. AU - Ferrucci, L. AU - Tracy, R. P. AU - Corti, M. C. AU - Wacholder, S. AU - Ettinger, W. H. AU - Heimovitz, H. AU - Cohen, H. J. AU - Wallace, R. PY - 1999 DA - 1999// TI - Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly JO - Am J Med VL - 106 UR - https://doi.org/10.1016/S0002-9343(99)00066-2 DO - 10.1016/S0002-9343(99)00066-2 ID - Harris1999 ER - TY - JOUR AU - Volpato, S. AU - Guralnik, J. M. AU - Ferrucci, L. AU - Balfour, J. AU - Chaves, P. AU - Fried, L. P. AU - Harris, T. B. PY - 2001 DA - 2001// TI - Cardiovascular disease, interleukin-6, and risk of mortality in older women: the women's health and aging study JO - Circulation VL - 103 UR - https://doi.org/10.1161/01.CIR.103.7.947 DO - 10.1161/01.CIR.103.7.947 ID - Volpato2001 ER - TY - JOUR AU - Bruunsgaard, H. AU - Andersen-Ranberg, K. AU - Hjelmborg, J. B. AU - Pedersen, B. K. AU - Jeune, B. PY - 2003 DA - 2003// TI - Elevated levels of tumor necrosis factor alpha and mortality in centenarians JO - Am J Med VL - 115 UR - https://doi.org/10.1016/S0002-9343(03)00329-2 DO - 10.1016/S0002-9343(03)00329-2 ID - Bruunsgaard2003 ER - TY - JOUR AU - Bruunsgaard, H. AU - Ladelund, S. AU - Pedersen, A. N. AU - Schroll, M. AU - Jørgensen, T. AU - Pedersen, B. K. PY - 2003 DA - 2003// TI - Predicting death from tumor necrosis factor-alpha and interleukin-6 in 80-year-old people JO - Clin Exp Immunol VL - 132 UR - https://doi.org/10.1046/j.1365-2249.2003.02137.x DO - 10.1046/j.1365-2249.2003.02137.x ID - Bruunsgaard2003 ER - TY - JOUR AU - Reuben, D. B. AU - Cheh, A. I. AU - Harris, T. B. AU - Ferrucci, L. AU - Rowe, J. W. AU - Tracy, R. P. AU - Seeman, T. E. PY - 2002 DA - 2002// TI - Peripheral blood markers of inflammation predict mortality and functional decline in high-functioning community-dwelling older persons JO - J Am Geriatr Soc VL - 50 UR - https://doi.org/10.1046/j.1532-5415.2002.50157.x DO - 10.1046/j.1532-5415.2002.50157.x ID - Reuben2002 ER - TY - JOUR AU - Mysliwska, J. AU - Bryl, E. AU - Foerster, J. AU - Mysliwski PY - 1998 DA - 1998// TI - A. Increase of interleukin 6 and decrease of interleukin 2 production during the ageing process are influenced by the health status JO - Mech Ageing Dev VL - 100 UR - https://doi.org/10.1016/S0047-6374(97)00154-1 DO - 10.1016/S0047-6374(97)00154-1 ID - Mysliwska1998 ER - TY - JOUR AU - Fried, L. P. AU - Tangen, C. M. AU - Walston, J. AU - Newman, A. B. AU - Hirsch, C. AU - Gottdiener, J. AU - Seeman, T. AU - Tracy, R. AU - Kop, W. J. AU - Burke, G. AU - McBurnie, M. A. PY - 2001 DA - 2001// TI - Frailty in older adults: evidence for a phenotype JO - J Gerontol A Biol Sci Med Sci VL - 56 UR - https://doi.org/10.1093/gerona/56.3.M146 DO - 10.1093/gerona/56.3.M146 ID - Fried2001 ER - TY - JOUR AU - Hamerman, D. PY - 1999 DA - 1999// TI - Toward an understanding of frailty JO - Ann Intern Med VL - 130 UR - https://doi.org/10.7326/0003-4819-130-11-199906010-00022 DO - 10.7326/0003-4819-130-11-199906010-00022 ID - Hamerman1999 ER - TY - JOUR AU - Roubenoff, R. AU - Hughes, V. PY - 2000 DA - 2000// TI - Sarcopenia: current concepts JO - J Gerontol A Biol Sci Med Sci VL - 55 UR - https://doi.org/10.1093/gerona/55.12.M716 DO - 10.1093/gerona/55.12.M716 ID - Roubenoff2000 ER - TY - JOUR AU - Brown, W. PY - 1972 DA - 1972// TI - A method for estimating the number of motor units in thenar muscles and the changes in motor unit count with aging JO - J Neurosurg Psych VL - 35 UR - https://doi.org/10.1136/jnnp.35.6.845 DO - 10.1136/jnnp.35.6.845 ID - Brown1972 ER - TY - JOUR AU - Roubenoff, R. PY - 2003 DA - 2003// TI - Catabolism of aging: is it an inflammatory process? JO - Curr Opin Clin Nutr Metab Care VL - 6 ID - Roubenoff2003 ER - TY - JOUR AU - Pedersen, M. AU - Bruunsgaard, H. AU - Weis, N. AU - Hendel, H. W. AU - Andreassen, B. U. AU - Eldrup, E. AU - Dela, F. AU - Pedersen, B. K. PY - 2003 DA - 2003// TI - Circulating levels of TNF-alpha and IL-6-relation to truncal fat mass and muscle mass in healthy elderly individuals and in patients with type-2 diabetes JO - Mech Ageing Dev VL - 124 UR - https://doi.org/10.1016/S0047-6374(03)00027-7 DO - 10.1016/S0047-6374(03)00027-7 ID - Pedersen2003 ER - TY - JOUR AU - Visser, M. AU - Pahor, M. AU - Taaffe, D. R. AU - Goodpaster, B. H. AU - Simonsick, E. M. AU - Newman, A. B. AU - Nevitt, M. AU - Harris, T. B. PY - 2002 DA - 2002// TI - Relationship of interleukin-6 and tumor necrosis factor-alpha with muscle mass and muscle strength in elderly men and women: the Health ABC study JO - J Gerontol A Biol Sci Med Sci VL - 57 UR - https://doi.org/10.1093/gerona/57.5.M326 DO - 10.1093/gerona/57.5.M326 ID - Visser2002 ER - TY - JOUR AU - Ferrucci, L. AU - Penninx, B. W. AU - Volpato, S. AU - Harris, T. B. AU - Bandeen-Roche, K. AU - Balfour, J. AU - Leveille, S. G. AU - Fried, L. P. AU - Md, J. M. PY - 2002 DA - 2002// TI - Change in muscle strength explains accelerated decline of physical function in older women with high interleukin-6 serum levels JO - J Am Geriatr Soc VL - 50 UR - https://doi.org/10.1046/j.1532-5415.2002.50605.x DO - 10.1046/j.1532-5415.2002.50605.x ID - Ferrucci2002 ER - TY - JOUR AU - Greiwe, J. S. AU - Cheng, B. AU - Rubin, D. C. AU - Yarasheski, K. E. AU - Semenkovich, C. F. PY - 2001 DA - 2001// TI - Resistance exercise decreases skeletal muscle tumor necrosis factor alpha in frail elderly humans JO - FASEB J VL - 15 UR - https://doi.org/10.1096/fj.00-0274com DO - 10.1096/fj.00-0274com ID - Greiwe2001 ER - TY - JOUR AU - Bruunsgaard, H. AU - Bjerregaard, E. AU - Schroll, M. AU - Pedersen, B. K. PY - 2004 DA - 2004// TI - Muscle strength following resistance training is inversely correlated with baseline levels of soluble tumor necrosis Factor receptors in the oldest old JO - J Am Geriatr Soc VL - 52 UR - https://doi.org/10.1111/j.1532-5415.2004.52061.x DO - 10.1111/j.1532-5415.2004.52061.x ID - Bruunsgaard2004 ER - TY - JOUR AU - Barbieri, M. AU - Ferrucci, L. AU - Ragno, E. AU - Corsi, A. AU - Bandinelli, S. AU - Bonafe, M. AU - Olivieri, F. AU - Giovagnetti, S. AU - Franceschi, C. AU - Guralnik, J. M. AU - Paolisso, G. PY - 2003 DA - 2003// TI - Chronic inflammation and the effect of IGF-I on muscle strength and power in older persons JO - Am J Physiol Endocrinol Metab VL - 284 UR - https://doi.org/10.1152/ajpendo.00319.2002 DO - 10.1152/ajpendo.00319.2002 ID - Barbieri2003 ER - TY - JOUR AU - Cappola, A. R. AU - Xue, Q. L. AU - Ferrucci, L. AU - Guralnik, J. M. AU - Volpato, S. AU - Fried, L. P. PY - 2003 DA - 2003// TI - Insulin-like growth factor I and interleukin-6 contribute synergistically to disability and mortality in older women JO - J Clin Endocrinol Metab VL - 88 UR - https://doi.org/10.1210/jc.2002-021694 DO - 10.1210/jc.2002-021694 ID - Cappola2003 ER - TY - JOUR AU - Kern, P. A. AU - Ranganathan, S. AU - Li, C. AU - Wood, L. AU - Ranganathan, G. PY - 2001 DA - 2001// TI - Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance JO - Am J Physiol Endocrinol Metab VL - 280 ID - Kern2001 ER - TY - JOUR AU - Senn, J. AU - Klover, P. AU - Nowak, I. AU - Mooney, R. PY - 2002 DA - 2002// TI - Interleukin-6 induces cellular insulin resistance in hepatocytes JO - Diabetes VL - 51 UR - https://doi.org/10.2337/diabetes.51.12.3391 DO - 10.2337/diabetes.51.12.3391 ID - Senn2002 ER - TY - JOUR AU - Hotamisligil, G. S. AU - Shargill, N. S. AU - Spiegelman, B. M. PY - 1993 DA - 1993// TI - Adipose expression of tumor necrosis factor-alpha: direct role in obesity linked insulin resistance JO - Science VL - 259 UR - https://doi.org/10.1126/science.7678183 DO - 10.1126/science.7678183 ID - Hotamisligil1993 ER - TY - JOUR AU - Kereiakes, D. J. AU - Willerson, J. T. PY - 2003 DA - 2003// TI - Metabolic syndrome epidemic JO - Circulation VL - 108 UR - https://doi.org/10.1161/01.CIR.0000093203.00632.2B DO - 10.1161/01.CIR.0000093203.00632.2B ID - Kereiakes2003 ER - TY - JOUR AU - Calle, E. E. AU - Thun, M. J. AU - Petrelli, J. M. AU - Rodriguez, C. AU - Heath, C. W. PY - 1999 DA - 1999// TI - Body-mass index and mortality in a prospective cohort of U.S. adults JO - N Engl J Med VL - 341 UR - https://doi.org/10.1056/NEJM199910073411501 DO - 10.1056/NEJM199910073411501 ID - Calle1999 ER - TY - JOUR AU - Neel, J. V. PY - 1962 DA - 1962// TI - Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"? JO - Am J Hum Genet VL - 14 ID - Neel1962 ER - TY - JOUR AU - Diamond, J. PY - 2003 DA - 2003// TI - The double puzzle of diabetes JO - Nature VL - 423 UR - https://doi.org/10.1038/423599a DO - 10.1038/423599a ID - Diamond2003 ER - TY - JOUR AU - Lazar, M. A. PY - 2005 DA - 2005// TI - How obesity causes diabetes: not a tall tale JO - Science VL - 307 UR - https://doi.org/10.1126/science.1104342 DO - 10.1126/science.1104342 ID - Lazar2005 ER - TY - JOUR AU - Tracy, R. O. PY - 2003 DA - 2003// TI - Inflammation, the metabolic syndrome and cardiovascular risk JO - Int Clin Pract Suppl VL - 134 ID - Tracy2003 ER - TY - JOUR AU - Das, U. PY - 2004 DA - 2004// TI - Metabolic syndrome X: an inflammatory condition? JO - Curr Hypertens Rep VL - 6 UR - https://doi.org/10.1007/s11906-004-0014-8 DO - 10.1007/s11906-004-0014-8 ID - Das2004 ER - TY - JOUR AU - Kern, P. A. AU - Saghizadeh, M. AU - Ong, J. M. AU - Bosch, R. J. AU - Deem, R. AU - Simsolo, R. B. PY - 1995 DA - 1995// TI - The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase JO - J Clin Invest VL - 95 UR - https://doi.org/10.1172/JCI117899 DO - 10.1172/JCI117899 ID - Kern1995 ER - TY - JOUR AU - Yudkin, J. S. AU - Stehouwer, C. D. AU - Emeis, J. J. AU - Coppack, S. W. PY - 1999 DA - 1999// TI - C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue? JO - Arterioscler Thromb Vasc Biol VL - 19 UR - https://doi.org/10.1161/01.ATV.19.4.972 DO - 10.1161/01.ATV.19.4.972 ID - Yudkin1999 ER - TY - JOUR AU - Mohamed-Ali, V. AU - Goodrick, S. AU - Rawesh, A. AU - Katz, D. R. AU - Miles, J. M. AU - Yudkin, J. S. AU - Klein, S. AU - Coppack, S. W. PY - 1997 DA - 1997// TI - Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-α, in vivo JO - J Clin Endocrinol Metab VL - 82 ID - Mohamed-Ali1997 ER - TY - JOUR AU - Lundgren, C. H. AU - Brown, S. L. AU - Nordt, T. K. AU - Sobel, B. E. AU - Fujii, S. PY - 1996 DA - 1996// TI - Elaboration of type-1 plasminogen activator inhibitor from adipocytes. A potential pathogenetic link between obesity and cardiovascular disease JO - Circulation VL - 93 UR - https://doi.org/10.1161/01.CIR.93.1.106 DO - 10.1161/01.CIR.93.1.106 ID - Lundgren1996 ER - TY - JOUR AU - Curat, C. A. AU - Miranville, A. AU - Sengenes, C. AU - Diehl, M. AU - Tonus, C. AU - Busse, R. AU - Bouloumie, A. PY - 2004 DA - 2004// TI - From blood monocytes to adipose tissue-resident macrophages: induction of diapedesis by human mature adipocytes JO - Diabetes VL - 53 UR - https://doi.org/10.2337/diabetes.53.5.1285 DO - 10.2337/diabetes.53.5.1285 ID - Curat2004 ER - TY - JOUR AU - Perseghin, G. AU - Petersen, K. AU - Shulman, G. I. PY - 2003 DA - 2003// TI - Cellular mechanism of insulin resistance: potential links with inflammation JO - Int J Obes Relat Metab Disord VL - 3 UR - https://doi.org/10.1038/sj.ijo.0802491 DO - 10.1038/sj.ijo.0802491 ID - Perseghin2003 ER - TY - JOUR AU - Haffner, S. M. PY - 2003 DA - 2003// TI - Insulin resistance, inflammation, and the prediabetic state JO - Am J Cardiol VL - 92 UR - https://doi.org/10.1016/S0002-9149(03)00612-X DO - 10.1016/S0002-9149(03)00612-X ID - Haffner2003 ER - TY - JOUR AU - Dandona, P. AU - Aljada, A. AU - Bandyopadhyay, A. PY - 2004 DA - 2004// TI - Inflammation: the link between insulin resistance, obesity and diabetes JO - Trends Immunol VL - 25 UR - https://doi.org/10.1016/j.it.2003.10.013 DO - 10.1016/j.it.2003.10.013 ID - Dandona2004 ER - TY - JOUR AU - Spranger, J. AU - Kroke, A. AU - Mohlig, M. AU - Hoffmann, K. AU - Bergmann, M. M. AU - Ristow, M. AU - Boeing, H. AU - Pfeiffer, A. F. PY - 2003 DA - 2003// TI - Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study JO - Diabetes VL - 52 UR - https://doi.org/10.2337/diabetes.52.3.812 DO - 10.2337/diabetes.52.3.812 ID - Spranger2003 ER - TY - JOUR AU - Festa, A. AU - Hanley, A. J. AU - Tracy, R. P. AU - D'Agostino, R. AU - Haffner, S. M. PY - 2003 DA - 2003// TI - Inflammation in the prediabetic state is related to increased insulin resistance rather than decreased insulin secretion JO - Circulation VL - 108 UR - https://doi.org/10.1161/01.CIR.0000091339.70120.53 DO - 10.1161/01.CIR.0000091339.70120.53 ID - Festa2003 ER - TY - JOUR AU - Temelkova-Kurktschiev, T. AU - Siegert, G. AU - Bergmann, S. AU - Henkel, E. AU - Koehler, C. AU - Jaross, W. AU - Hanefeld, M. PY - 2002 DA - 2002// TI - Subclinical inflammation is strongly related to insulin resistance but not to impaired insulin secretion in a high risk population for diabetes JO - Metabolism VL - 51 UR - https://doi.org/10.1053/meta.2002.32804 DO - 10.1053/meta.2002.32804 ID - Temelkova-Kurktschiev2002 ER - TY - JOUR AU - Abbatecola, A. M. AU - Ferrucci, L. AU - Grella, R. AU - Bandinelli, S. AU - Bonafe, M. AU - Barbieri, M. AU - Corsi, A. M. AU - Lauretani, F. AU - Franceschi, C. AU - Paolisso, G. PY - 2004 DA - 2004// TI - Diverse effect of inflammatory markers on insulin resistance and insulin-resistance syndrome in the elderly JO - J Am Geriatr Soc VL - 52 UR - https://doi.org/10.1111/j.1532-5415.2004.52112.x DO - 10.1111/j.1532-5415.2004.52112.x ID - Abbatecola2004 ER - TY - JOUR AU - Hotamisligil, G. S. AU - Budavari, A. AU - Murray, D. AU - Spiegelman, B. M. PY - 1994 DA - 1994// TI - Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-α JO - J Clin Invest VL - 94 UR - https://doi.org/10.1172/JCI117495 DO - 10.1172/JCI117495 ID - Hotamisligil1994 ER - TY - JOUR AU - Kubaszek, A. AU - Pihlajamaki, J. AU - Komarovski, V. AU - Lindi, V. AU - Lindstrom, J. AU - Eriksson, J. AU - Valle, T. T. AU - Hamalainen, H. AU - Ilanne-Parikka, P. AU - Keinanen-Kiukaanniemi, S. AU - Tuomilehto, J. AU - Uusitupa, M. AU - Laakso, M. PY - 2003 DA - 2003// TI - Finnish Diabetes Prevention Study. Promoter polymorphisms of the TNF-alpha (G-308A) and IL-6 (C-174G) genes predict the conversion from impaired glucose tolerance to type 2 diabetes: the Finnish Diabetes Prevention Study JO - Diabetes VL - 52 UR - https://doi.org/10.2337/diabetes.52.7.1872 DO - 10.2337/diabetes.52.7.1872 ID - Kubaszek2003 ER - TY - JOUR AU - Aljada, A. AU - Ghanim, H. AU - Mohanty, P. AU - Kapur, N. AU - Dandona, P. PY - 2002 DA - 2002// TI - Insulin inhibits the pro-inflammatory transcription factor early growth response gene-1 (Egr)-1 expression in mononuclear cells (MNC) and reduces plasma tissue factor (TF) and plasminogen activator inhibitor-1 (PAI-1) concentrations JO - J Clin Endocrinol Metab VL - 87 UR - https://doi.org/10.1210/jcem.87.3.8462 DO - 10.1210/jcem.87.3.8462 ID - Aljada2002 ER - TY - JOUR AU - Das, M. AU - Gabriely, I. AU - Barzilai, N. PY - 2004 DA - 2004// TI - Caloric restriction, body fat and ageing in experimental models JO - Obes Rev VL - 5 UR - https://doi.org/10.1111/j.1467-789X.2004.00115.x DO - 10.1111/j.1467-789X.2004.00115.x ID - Das2004 ER - TY - JOUR AU - De Pinho, R. A. PY - 2000 DA - 2000// TI - The age of cancer JO - Nature VL - 408 UR - https://doi.org/10.1038/35041694 DO - 10.1038/35041694 ID - De Pinho2000 ER - TY - JOUR AU - Caruso, C. AU - Lio, D. AU - Cavallone, L. AU - Franceschi, C. PY - 2004 DA - 2004// TI - Aging, Longevity, Inflammation, and Cancer JO - Ann NY Acad Sci VL - 1028 UR - https://doi.org/10.1196/annals.1322.001 DO - 10.1196/annals.1322.001 ID - Caruso2004 ER - TY - JOUR AU - Repetto, L. AU - Venturino, A. AU - Fratino, L. AU - Serraino, D. AU - Troisi, G. AU - Gianni, W. AU - Pietropaolo, M. PY - 2003 DA - 2003// TI - Geriatric oncology: a clinical approach to the older patient with cancer JO - Eur J Cancer VL - 39 UR - https://doi.org/10.1016/S0959-8049(03)00062-5 DO - 10.1016/S0959-8049(03)00062-5 ID - Repetto2003 ER - TY - JOUR AU - Thun, M. J. AU - Henley, S. J. AU - Gansler, T. PY - 2004 DA - 2004// TI - Inflammation and cancer: an epidemiological perspective JO - Novartis Found Synp VL - 256 ID - Thun2004 ER - TY - JOUR AU - Macarthur, M. AU - Hold, G. L. AU - El-Omar, E. M. PY - 2004 DA - 2004// TI - Inflammation and Cancer II. Role of chronic inflammation and cytokine gene polymorphisms in the pathogenesis of gastrointestinal malignancy JO - Am J Physiol Gastointest Liver Physiol VL - 286 UR - https://doi.org/10.1152/ajpgi.00475.2003 DO - 10.1152/ajpgi.00475.2003 ID - Macarthur2004 ER - TY - JOUR AU - Brigati, C. AU - Noonan, D. M. AU - Albini, A. AU - Benelli, R. PY - 2002 DA - 2002// TI - Tumors and inflammatory infiltrates: friends or foes? JO - Clin Exp Metastasis VL - 19 UR - https://doi.org/10.1023/A:1015587423262 DO - 10.1023/A:1015587423262 ID - Brigati2002 ER - TY - JOUR AU - Balkwill, F. AU - Mantovani, A. PY - 2001 DA - 2001// TI - Inflammation and cancer: back to Virchow JO - Lancet VL - 357 UR - https://doi.org/10.1016/S0140-6736(00)04046-0 DO - 10.1016/S0140-6736(00)04046-0 ID - Balkwill2001 ER - TY - JOUR AU - Erlinger, T. P. AU - Platz, E. A. AU - Rifai, N. AU - Helzlsouer, K. J. PY - 2004 DA - 2004// TI - C-reactive protein and the risk of incident colorectal cancer JO - JAMA VL - 291 UR - https://doi.org/10.1001/jama.291.5.585 DO - 10.1001/jama.291.5.585 ID - Erlinger2004 ER - TY - JOUR AU - McMillan, D. C. AU - Canna, K. AU - McArdle, C. S. PY - 2003 DA - 2003// TI - Systemic inflammatory response predicts survival following curative resection of colorectal cancer JO - Br J Surg VL - 90 UR - https://doi.org/10.1002/bjs.4038 DO - 10.1002/bjs.4038 ID - McMillan2003 ER - TY - JOUR AU - Bonafe, M. AU - Olivieri, F. AU - Cavallone, L. AU - Giovagnetti, S. AU - Mayegiani, F. AU - Cardelli, M. AU - Pieri, C. AU - Marra, M. AU - Antonicelli, R. AU - Lisa, R. AU - Rizzo, M. R. AU - Paolisso, G. AU - Monti, D. AU - Franceschi, C. PY - 2001 DA - 2001// TI - A gender – dependent genetic predisposition to produce high levels of IL-6 is detrimental for longevity JO - Eur J Immunol VL - 31 UR - https://doi.org/3.0.CO;2-X DO - 3.0.CO;2-X ID - Bonafe2001 ER - TY - JOUR AU - Lio, D. AU - Scola, L. AU - Crivello, A. AU - Colonna-Romano, G. AU - Candore, G. AU - Bonafe, M. AU - Cavallone, L. AU - Franceschi, C. AU - Caruso, C. PY - 2002 DA - 2002// TI - Gender-specific association between -1082 IL-10 promoter polymorphism and longevity JO - Genes Immun VL - 3 UR - https://doi.org/10.1038/sj.gene.6363827 DO - 10.1038/sj.gene.6363827 ID - Lio2002 ER - TY - JOUR AU - Lio, D. AU - Scola, L. AU - Crivello, A. AU - Colonna-Romano, G. AU - Candore, G. AU - Bonafe, M. AU - Cavallone, L. AU - Marchegiani, F. AU - Olivieri, F. AU - Franceschi, C. AU - Caruso, C. PY - 2003 DA - 2003// TI - Inflammation, genetics, and longevity: further studies on the protective effects in men of IL-10 -1082 promoter SNP and its interaction with TNF-alpha -308 promoter SNP JO - J Med Genet VL - 40 UR - https://doi.org/10.1136/jmg.40.4.296 DO - 10.1136/jmg.40.4.296 ID - Lio2003 ER - TY - JOUR AU - Caruso, C. AU - Candore, G. AU - Colonna Romano, G. AU - Lio, D. AU - Bonafe, M. AU - Valensin, S. AU - Franceschi, C. PY - 2000 DA - 2000// TI - HLA, aging, and longevity: a critical reappraisal JO - Hum Immunol VL - 61 UR - https://doi.org/10.1016/S0198-8859(00)00168-3 DO - 10.1016/S0198-8859(00)00168-3 ID - Caruso2000 ER - TY - JOUR AU - Shin, H. D. AU - Park, B. L. AU - Kim, L. H. AU - Jung, J. H. AU - Kim, J. Y. AU - Yoon, J. H. AU - Kim, Y. J. AU - Lee, H. S. PY - 2003 DA - 2003// TI - Interleukin 10 haplotype associated with increased risk of hepatocellular carcinoma JO - Hum Mol Genet VL - 12 UR - https://doi.org/10.1093/hmg/ddg104 DO - 10.1093/hmg/ddg104 ID - Shin2003 ER - TY - JOUR AU - Hussain, S. P. AU - Hofseth, L. J. AU - Harris, C. C. PY - 2003 DA - 2003// TI - Radical causes of cancer JO - Nature Rev Cancer VL - 3 UR - https://doi.org/10.1038/nrc1046 DO - 10.1038/nrc1046 ID - Hussain2003 ER - TY - JOUR AU - Szlosarek, P. W. AU - Balkwill, F. R. PY - 2003 DA - 2003// TI - Tumor necrosis factor alpha: a potential target for the therapy of solid tumors JO - Lancet Oncol VL - 4 UR - https://doi.org/10.1016/S1470-2045(03)01196-3 DO - 10.1016/S1470-2045(03)01196-3 ID - Szlosarek2003 ER - TY - JOUR AU - Braunwald, E. PY - 1997 DA - 1997// TI - Shattuck lecture – cardiovascular medicine at the turn of the millennium: triumphs, concerns, and opportunities JO - N Engl J Med VL - 337 UR - https://doi.org/10.1056/NEJM199711063371906 DO - 10.1056/NEJM199711063371906 ID - Braunwald1997 ER - TY - JOUR AU - Libby, P. AU - Ridker, P. M. AU - Maseri, A. PY - 2002 DA - 2002// TI - Inflammation and atherosclerosis JO - Circulation VL - 105 UR - https://doi.org/10.1161/hc0902.104353 DO - 10.1161/hc0902.104353 ID - Libby2002 ER - TY - JOUR AU - Ross, R. PY - 1999 DA - 1999// TI - Atherosclerosis: An inflammatory disease JO - N Engl J Med VL - 340 UR - https://doi.org/10.1056/NEJM199901143400207 DO - 10.1056/NEJM199901143400207 ID - Ross1999 ER - TY - JOUR AU - Lusis, A. J. PY - 2000 DA - 2000// TI - Atherosclerosis JO - Nature VL - 407 UR - https://doi.org/10.1038/35025203 DO - 10.1038/35025203 ID - Lusis2000 ER - TY - JOUR AU - Libby, P. PY - 2002 DA - 2002// TI - Inflammation in atherosclerosis JO - Nature VL - 420 UR - https://doi.org/10.1038/nature01323 DO - 10.1038/nature01323 ID - Libby2002 ER - TY - JOUR AU - Rifai, N. AU - Ridker, P. M. PY - 2001 DA - 2001// TI - Proposed cardiovascular risk assessment algorithm using high-sensitivity C-reactive protein and lipid screening JO - Clin Chem VL - 47 ID - Rifai2001 ER - TY - JOUR AU - Ridker, P. M. AU - Rifai, N. AU - Stampfer, M. J. AU - Hennekens, C. H. PY - 2000 DA - 2000// TI - Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men JO - Circulation VL - 101 UR - https://doi.org/10.1161/01.CIR.101.15.1767 DO - 10.1161/01.CIR.101.15.1767 ID - Ridker2000 ER - TY - JOUR AU - Hansson, G. K. AU - Libby, P. AU - Schonbeck, U. AU - Yan, Z. Q. PY - 2002 DA - 2002// TI - Innate and aquired immunity in the pathogenesis of atherosclerosis JO - Circulation Res VL - 91 UR - https://doi.org/10.1161/01.RES.0000029784.15893.10 DO - 10.1161/01.RES.0000029784.15893.10 ID - Hansson2002 ER - TY - JOUR AU - Ridker, P. M. AU - Hennekens, C. H. AU - Buring, J. E. AU - Rifai, N. PY - 2000 DA - 2000// TI - C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women JO - N Engl J Med VL - 342 UR - https://doi.org/10.1056/NEJM200003233421202 DO - 10.1056/NEJM200003233421202 ID - Ridker2000 ER - TY - JOUR AU - Ridker, P. M. AU - Rifai, N. AU - Rose, L. AU - Buring, J. E. AU - Cook, N. R. PY - 2002 DA - 2002// TI - Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events JO - N Engl J Med VL - 347 UR - https://doi.org/10.1056/NEJMoa021993 DO - 10.1056/NEJMoa021993 ID - Ridker2002 ER - TY - JOUR AU - Di Iorio, A. AU - Ferrucci, L. AU - Sparvieri, E. AU - Cherubini, A. AU - Volpato, S. AU - Corsi, A. AU - Bonafe, M. AU - Franceschi, C. AU - Abate, G. AU - Paganelli, R. PY - 2003 DA - 2003// TI - Serum IL-1beta levels in health and disease: a population-based study. 'The InCHIANTI study' JO - Cytokine VL - 22 UR - https://doi.org/10.1016/S1043-4666(03)00152-2 DO - 10.1016/S1043-4666(03)00152-2 ID - Di Iorio2003 ER - TY - JOUR AU - Barbieri, M. AU - Ferrucci, L. AU - Corsi, A. M. AU - Macchi, C. AU - Lauretani, F. AU - Bonafe, M. AU - Olivieri, F. AU - Giovagnetti, S. AU - Franceschi, C. AU - Paolisso, G. PY - 2003 DA - 2003// TI - Is chronic inflammation a determinant of blood pressure in the elderly? JO - Am J Hypertens VL - 16 UR - https://doi.org/10.1016/S0895-7061(03)00861-6 DO - 10.1016/S0895-7061(03)00861-6 ID - Barbieri2003 ER - TY - JOUR AU - Nabel, E. G. PY - 2003 DA - 2003// TI - Cardiovascular disease JO - N Engl J Med VL - 349 UR - https://doi.org/10.1056/NEJMra035098 DO - 10.1056/NEJMra035098 ID - Nabel2003 ER - TY - JOUR AU - Andreotti, F. AU - Porto, I. AU - Crea, F. AU - Maseri, A. PY - 2002 DA - 2002// TI - Inflammatory gene polymorphisms and ischaemic heart disease: review of population association studies JO - Heart VL - 87 UR - https://doi.org/10.1136/heart.87.2.107 DO - 10.1136/heart.87.2.107 ID - Andreotti2002 ER - TY - JOUR AU - Stephens, J. W. AU - Humphries, S. E. PY - 2003 DA - 2003// TI - The molecular genetics of cardiovascular disease: clinical implications JO - J Intern Med VL - 253 UR - https://doi.org/10.1046/j.1365-2796.2003.01104.x DO - 10.1046/j.1365-2796.2003.01104.x ID - Stephens2003 ER - TY - JOUR AU - Lio, D. AU - Candore, G. AU - Crivello, A. AU - Scola, L. AU - Colonna-Romano, L. AU - Cavallone, L. AU - Hoffmann, E. AU - Caruso, M. AU - Licastro, F. AU - Caldarera, C. M. AU - Branzi, A. AU - Franceschi, C. AU - Caruso, C. PY - 2004 DA - 2004// TI - Opposite effects of IL-10 gene polymorphisms in cardiovascular diseases and in successful ageing: genetic background of male centenarians is prospettive against coronary heart disease JO - J Med Genet VL - 41 UR - https://doi.org/10.1136/jmg.2004.019885 DO - 10.1136/jmg.2004.019885 ID - Lio2004 ER - TY - JOUR AU - Listì, F. AU - Candore, G. AU - Lio, D. AU - Cavallone, L. AU - Colonna-Romano, G. AU - Caruso, M. AU - Hoffmann, E. AU - Caruso, C. PY - 2004 DA - 2004// TI - Association between platelet endothelial cellular adhesion molecule 1 (PECAM-1/CD31) polymorphisms and acute myocardial infarction: a study in patients from Sicily JO - Eur J Immunogenet VL - 31 UR - https://doi.org/10.1111/j.1365-2370.2004.00464.x DO - 10.1111/j.1365-2370.2004.00464.x ID - Listì2004 ER - TY - JOUR AU - Licastro, F. AU - Chiappelli, M. AU - Caldarera, C. M. AU - Tampieri, C. AU - Nanni, S. AU - Gallina, M. AU - Branzi, A. PY - 2004 DA - 2004// TI - The concomitant presence of polymorphic alleles of interleukin-1beta, interleukin-6 and apolipoprotein E is associated with an increased risk of myocardial infarction in elderly men. Results from a pilot study JO - Mech Ageing Dev VL - 125 ID - Licastro2004 ER - TY - JOUR AU - Benagiano, M. AU - Azzurri, A. AU - Ciervo, A. AU - Amedei, A. AU - Tamburini, C. AU - Ferrari, M. AU - Telford, J. L. AU - Baldari, C. T. AU - Romagnani, S. AU - Cassone, A. AU - D'Elios, M. M. AU - Del Prete, G. PY - 2003 DA - 2003// TI - T helper type 1 lymphocytes drive inflammation in human atherosclerotic lesions. Proc Natl Acad Sci U S A JO - Epub VL - 100 ID - Benagiano2003 ER - TY - JOUR AU - Gupta, S. AU - Pablo, A. M. AU - Jiang, X. AU - Wang, N. AU - Tall, A. R. AU - Schindler, C. PY - 1997 DA - 1997// TI - IFN-gamma potentiates atherosclerosis in ApoE knock-out mice JO - J Clin Invest VL - 99 UR - https://doi.org/10.1172/JCI119465 DO - 10.1172/JCI119465 ID - Gupta1997 ER - TY - JOUR AU - Whitman, S. C. AU - Ravisankar, P. AU - Elam, H. AU - Daugherty, A. PY - 2000 DA - 2000// TI - Exogenous interferon-gamma enhances atherosclerosis in apolipoprotein E-/- mice JO - Am J Pathol VL - 157 UR - https://doi.org/10.1016/S0002-9440(10)64820-1 DO - 10.1016/S0002-9440(10)64820-1 ID - Whitman2000 ER - TY - JOUR AU - Hansson, G. K. PY - 2002 DA - 2002// TI - The B cell: a good guy in vascular disease? JO - Arterioscler Thromb Vasc Biol VL - 22 UR - https://doi.org/10.1161/01.ATV.0000015098.68671.1C DO - 10.1161/01.ATV.0000015098.68671.1C ID - Hansson2002 ER - TY - JOUR AU - Wick, G. AU - Knoflach, M. AU - Xu, Q. PY - 2004 DA - 2004// TI - Autoimmune and inflammatory mechanisms in atherosclerosis JO - Annu Rev Immunol VL - 22 UR - https://doi.org/10.1146/annurev.immunol.22.012703.104644 DO - 10.1146/annurev.immunol.22.012703.104644 ID - Wick2004 ER - TY - JOUR AU - Brookmeyer, R. AU - Gray, S. AU - Kawas, C. PY - 1998 DA - 1998// TI - Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset JO - Am J Public Health VL - 88 UR - https://doi.org/10.2105/AJPH.88.9.1337 DO - 10.2105/AJPH.88.9.1337 ID - Brookmeyer1998 ER - TY - JOUR AU - Selkoe, D. J. PY - 2001 DA - 2001// TI - Alzheimer's disease: genes, proteins, and therapy JO - Physiol Rev VL - 81 ID - Selkoe2001 ER - TY - JOUR AU - Ritchie, K. AU - Lovestone, S. PY - 2002 DA - 2002// TI - The dementias JO - Lancet VL - 360 UR - https://doi.org/10.1016/S0140-6736(02)11667-9 DO - 10.1016/S0140-6736(02)11667-9 ID - Ritchie2002 ER - TY - JOUR AU - McGeer, E. G. AU - McGeer, P. L. PY - 1998 DA - 1998// TI - The importance of inflammatory mechanisms in Alzheimer disease JO - Exp Geront VL - 33 UR - https://doi.org/10.1016/S0531-5565(98)00013-8 DO - 10.1016/S0531-5565(98)00013-8 ID - McGeer1998 ER - TY - JOUR AU - Licastro, F. PY - 2002 DA - 2002// TI - Genomics of immune molecules: early detection of cognitive decline and new therapeutic interventions JO - Expert Rev Neurotherapeutics VL - 2 UR - https://doi.org/10.1586/14737175.2.5.639 DO - 10.1586/14737175.2.5.639 ID - Licastro2002 ER - TY - JOUR AU - Lee, Y. B. AU - Nagai, A. AU - Kim, S. U. PY - 2002 DA - 2002// TI - Cytokines, chemokines, and cytokine receptors in human microglia JO - J Neurosci Res VL - 69 UR - https://doi.org/10.1002/jnr.10253 DO - 10.1002/jnr.10253 ID - Lee2002 ER - TY - JOUR AU - In t' Veld, B. A. AU - Ruitenberg, A. AU - Hofman, A. PY - 2001 DA - 2001// TI - Nonsteroidal antiinflammatory drugs and the risk of Alzheimer's disease JO - N Engl J Med VL - 345 UR - https://doi.org/10.1056/NEJMoa010178 DO - 10.1056/NEJMoa010178 ID - In t' Veld2001 ER - TY - JOUR AU - Vagnucci, A. H. AU - Li, W. W. PY - 2003 DA - 2003// TI - Alzheimer's disease and angiogenesis JO - Lancet VL - 361 UR - https://doi.org/10.1016/S0140-6736(03)12521-4 DO - 10.1016/S0140-6736(03)12521-4 ID - Vagnucci2003 ER - TY - JOUR AU - Schmidt, R. AU - Schmidt, H. AU - Curb, J. D. AU - Masaki, K. AU - White, L. R. AU - Launer, L. J. PY - 2002 DA - 2002// TI - Early inflammation and dementia: a 25-year follow-up of the Honolulu-Asia Aging Study JO - Ann Neurol VL - 52 UR - https://doi.org/10.1002/ana.10265 DO - 10.1002/ana.10265 ID - Schmidt2002 ER - TY - JOUR AU - Licastro, F. AU - Pedrini, S. AU - Caputo, L. AU - Annoni, G. AU - Davis, L. J. AU - Ferri, C. AU - Casadei, V. AU - Grimaldi, L. M. PY - 2000 DA - 2000// TI - Increased plasma levels of interleukin-1, interleukin-6 and alpha-1-antichymotrypsin in patients with Alzheimer's disease: peripheral inflammation or signals from the brain? JO - J Neuroimmunol VL - 103 UR - https://doi.org/10.1016/S0165-5728(99)00226-X DO - 10.1016/S0165-5728(99)00226-X ID - Licastro2000 ER - TY - JOUR AU - Licastro, F. AU - Pedrini, S. AU - Ferri, C. AU - Casadei, V. AU - Govoni, M. AU - Pession, A. AU - Sciacca, F. L. AU - Veglia, F. AU - Annoni, G. AU - Bonafe, M. AU - Olivieri, F. AU - Franceschi, C. AU - Grimaldi, L. M. PY - 2000 DA - 2000// TI - Gene polymorphism affecting alpha1-antichymotrypsin and interleukin-1 plasma levels increases Alzheimer's disease risk JO - Ann Neurol VL - 48 UR - https://doi.org/3.0.CO;2-G DO - 3.0.CO;2-G ID - Licastro2000 ER - TY - JOUR AU - De Luigi, A. AU - Fragiacomo, C. AU - Lucca, U. AU - Quadri, P. AU - Tettamanti, M. AU - Grazia De Simoni, M. PY - 2001 DA - 2001// TI - Inflammatory markers in Alzheimer's disease and multi-infarct dementia JO - Mech Ageing Dev VL - 122 UR - https://doi.org/10.1016/S0047-6374(01)00313-X DO - 10.1016/S0047-6374(01)00313-X ID - De Luigi2001 ER - TY - JOUR AU - Licastro, F. AU - Chiappelli, M. PY - 2003 DA - 2003// TI - Brain immune responses cognitive decline and dementia: relationship with phenotype expression and genetic background JO - Mech Ageing Dev VL - 124 UR - https://doi.org/10.1016/S0047-6374(03)00034-4 DO - 10.1016/S0047-6374(03)00034-4 ID - Licastro2003 ER - TY - JOUR AU - Licastro, F. AU - Grimaldi, L. M. AU - Bonafe, M. AU - Martina, C. AU - Olivieri, F. AU - Cavallone, L. AU - Giovanietti, S. AU - Masliah, E. AU - Franceschi, C. PY - 2003 DA - 2003// TI - Interleukin-6 gene alleles affect the risk of Alzheimer's disease and levels of the cytokine in blood and brain JO - Neurobiol Aging VL - 24 UR - https://doi.org/10.1016/S0197-4580(03)00013-7 DO - 10.1016/S0197-4580(03)00013-7 ID - Licastro2003 ER - TY - JOUR AU - Candore, G. AU - Balistreri, C. R. AU - Colonna-Romano, G. AU - Lio, D. AU - Caruso, C. PY - 2004 DA - 2004// TI - Major histocompatibility complex and sporadic Alzheimer's disease: a critical reappraisal JO - Exp Gerontol VL - 39 UR - https://doi.org/10.1016/j.exger.2003.10.027 DO - 10.1016/j.exger.2003.10.027 ID - Candore2004 ER - TY - JOUR AU - Akiyama, H. AU - Barger, S. AU - Barnum, S. AU - Bradt, B. AU - Bauer, J. AU - Cole, G. M. AU - Cooper, N. R. AU - Eikelenboom, P. AU - Emmerling, M. AU - Fiebich, B. L. AU - Finch, C. E. AU - Frautschy, S. AU - Griffin, W. S. AU - Hampel, H. AU - Hull, M. AU - Landreth, G. AU - Lue, L. AU - Mrak, R. AU - Mackenzie, I. R. AU - McGeer, P. L. AU - O'Banion, M. K. AU - Pachter, J. AU - Pasinetti, G. AU - Plata-Salaman, C. AU - Rogers, J. AU - Rydel, R. AU - Shen, Y. AU - Streit, W. AU - Strohmeyer, R. AU - Tooyoma, I. AU - Van Muiswinkel, F. L. AU - Veerhuis, R. AU - Walker, D. AU - Webster, S. AU - Wegrzyniak, B. AU - Wenk, G. AU - Wyss-Coray, T. PY - 2000 DA - 2000// TI - Inflammation and Alzheimer's disease JO - Neurobiol Aging VL - 21 UR - https://doi.org/10.1016/S0197-4580(00)00124-X DO - 10.1016/S0197-4580(00)00124-X ID - Akiyama2000 ER - TY - JOUR AU - Scola, L. AU - Licastro, F. AU - Chiappelli, M. AU - Franceschi, C. AU - Grimaldi, L. M. AU - Crivello, A. AU - Colonna-Romano, G. AU - Candore, G. AU - Lio, D. AU - Caruso, C. PY - 2003 DA - 2003// TI - Allele frequencies of +874T – > A single nucleotide polymorphism at the first intron of IFN-gamma gene in Alzheimer's disease patients JO - Aging Clin Exp Res VL - 15 UR - https://doi.org/10.1007/BF03324511 DO - 10.1007/BF03324511 ID - Scola2003 ER - TY - JOUR AU - Lio, D. AU - Licastro, F. AU - Scola, L. AU - Chiappelli, M. AU - Grimaldi, L. M. AU - Crivello, A. AU - Colonna-Romano, G. AU - Candore, G. AU - Franceschi, C. AU - Caruso, C. PY - 2003 DA - 2003// TI - Interleukin-10 promoter polymorphism in sporadic Alzheimer's disease JO - Genes Immun VL - 4 UR - https://doi.org/10.1038/sj.gene.6363964 DO - 10.1038/sj.gene.6363964 ID - Lio2003 ER - TY - JOUR AU - McGeer, P. L. AU - McGeer, E. G. PY - 2001 DA - 2001// TI - Polymorphisms in inflammatory genes and the risk of Alzheimer disease JO - Arch Neurol VL - 58 UR - https://doi.org/10.1001/archneur.58.11.1790 DO - 10.1001/archneur.58.11.1790 ID - McGeer2001 ER - TY - BOOK AU - Nesse, R. M. AU - Williams, G. C. PY - 1995 DA - 1995// TI - Evolution and Healing. The New Science of Darwinian Medicine PB - Nicolson CY - UK ID - Nesse1995 ER - TY - JOUR AU - Brod, S. A. PY - 2000 DA - 2000// TI - Unregulated inflammation shortens human functional longevity JO - Inflamm Res VL - 49 UR - https://doi.org/10.1007/s000110050632 DO - 10.1007/s000110050632 ID - Brod2000 ER - TY - JOUR AU - Franceschi, C. AU - Olivieri, F. AU - Marchegiani, F. AU - Cardelli, M. AU - Cavallone, L. AU - Capri, M. AU - Salvioli, S. AU - Valensin, S. AU - De Benedictis, G. AU - Di Iorio, A. AU - Caruso, C. AU - Paolisso, G. AU - Monti, D. PY - 2005 DA - 2005// TI - Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians JO - Mech Ageing Dev VL - 126 UR - https://doi.org/10.1016/j.mad.2004.08.028 DO - 10.1016/j.mad.2004.08.028 ID - Franceschi2005 ER - TY - JOUR AU - Caruso, C. AU - Candore, G. AU - Colonna-Romano, G. AU - Lio, D. AU - Franceschi, C. PY - 2005 DA - 2005// TI - Inflammation and life-span JO - Science VL - 307 UR - https://doi.org/10.1126/science.307.5707.208 DO - 10.1126/science.307.5707.208 ID - Caruso2005 ER - TY - JOUR AU - Wick, G. AU - Berger, P. AU - Jansen-Durr, P. AU - Grubeck-Loebenstein, B. PY - 2003 DA - 2003// TI - A Darwinian-evolutionary concept of age-related diseases JO - Exp Gerontol VL - 38 UR - https://doi.org/10.1016/S0531-5565(02)00161-4 DO - 10.1016/S0531-5565(02)00161-4 ID - Wick2003 ER - TY - JOUR AU - Mariani, L. AU - Turchetti, G. AU - Franceschi, C. PY - 2003 DA - 2003// TI - Chronic antigenic stress, immunosenescence and human survivorship over the 3 last centuries: heuristic value of a mathematical model JO - Mech Ageing Dev VL - 124 UR - https://doi.org/10.1016/S0047-6374(03)00022-8 DO - 10.1016/S0047-6374(03)00022-8 ID - Mariani2003 ER - TY - JOUR AU - Balistreri, C. R. AU - Candore, G. AU - Colonna-Romano, G. AU - Lio, D. AU - Caruso, M. AU - Hoffmann, E. AU - Franceschi, C. AU - Caruso, C. PY - 2004 DA - 2004// TI - Role of Toll-like receptor 4 in acute myocardial infarction and longevity JO - JAMA VL - 292 ID - Balistreri2004 ER -