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Table 2 Characteristics of the immune risk phenotype

From: Role of persistent CMV infection in configuring T cell immunity in the elderly

CD4:8 ratio < 1
poor T cell proliferative responses to mitogens
increased CD8+CD28-negative and CD8+CD57+ cells
low B cells count
CMV-seropositivity
clonal expansions of CD8 cells carrying receptors for CMV
high proportion of dysfunctional cells amongst the CMV-specific CD8 cells