Table 2 Characteristics of the immune risk phenotype
From: Role of persistent CMV infection in configuring T cell immunity in the elderly
CD4:8 ratio < 1 |
poor T cell proliferative responses to mitogens |
increased CD8+CD28-negative and CD8+CD57+ cells |
low B cells count |
CMV-seropositivity |
clonal expansions of CD8 cells carrying receptors for CMV |
high proportion of dysfunctional cells amongst the CMV-specific CD8 cells |