Skip to main content

Table 5 Laboratory parameter elevationsSelected results, patients <45 years

From: Evidence of accelerated ageing in clinical drug addiction from immune, hepatic and metabolic biomarkers

PARAMETER

Addicts†

Medical†

%'s*

OR

CI

P

Age <45 Years

739/798

5834/11295

92.6%/51.7%

11.72

8.90–15.47

<0.0001

Body Mass Index >25

148/297

35/53

33.3%/39.8%

0.75

0.46–1.24

N.S.

CRP > 6 IU/l

81/73

490/811

52.6%/37.7%

1.84

1.30–2.60

<0.0005

ESR>30 mm/hr

13/155

49/1159

7.7%/4.1%

1.98

1.00–3.87

<0.05

Globulins >35. g/dl

90/519

503/4930

14.8%/9.3%

1.70

1.32–2.18

<0.0001

Albumin > 42 g/dl

345/264

3000/2433

56.7%/55.2%

1.06

0.89–1.26

N.S.

Globulin/Albumin Ratio >0.9

90/519

503/4930

14.8%/9.3%

1.69

1.21–2.21

<0.002

Albumin/Globulin Ratio >1.8

57/552

495/4938

9.4%/9.1%

1.03

0.76–1.39

N.S.

Lymphocytes >2.5 × 10(9)/l

224/377

1281/2748

37.3%/31.8%

1.27

1.06–1.53

<0.01

ALT > 90 IU/l

105/505

504/4920

17.2%/9.3%

2.03

1.60–2.57

<0.0001

Cholesterol > 4.2 mmol/l

347/263

3593/1872

56.9%/65.8%

0.67

0.56–0.80

<0.0001

Creatinine > 100 mcmol/l

59/679

272/5159

8.0%/5.0%

1.65

1.22–2.23

<0.001

Urea > 5 mmol/l

227/381

1588/3727

37.3%/29.9%

1.41

1.17–1.67

<0.0002

Urea/Creatinine Ratio >6.5

81/658

288/5140

11.0%/5.3%

2.78

2.11–3.65

<0.0001

Creatinine/Urea >22

134/605

1251/4177

18.1%/23.0%

0.74

0.60–0.91

<0.005

IGF1 >30 nmol/l

19/40

21/162

32.2%/11.5%

3.66

1.70–7.91

<0.0002

DHEAS >6 noml/l

30/40

57/109

42.9%/34.3%

1.54

0.78–2.64

N.S.

  1. † – Cells in these columns represent the numbers greater and less than the defined cut-off point.
  2. * – Relates to Percentages in Addicts Vs. Medical Patients