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Table 3 Genotype frequency distribution of the three polymorphisms

From: Endothelial nitric oxide synthase gene polymorphisms and cardiovascular damage in hypertensive subjects: an Italian case-control study

  

Normotensives n. 67

Hypertensives n. 127

p<

G894T

GG

(19/67) 28%

(45/127) 35.4%

n.s.

 

GT

(41/67) 61%

(70/127) 55.1%

n.s.

 

TT

(7/67) 11%

(12/127) 9.5%

n.s.

 

GT+TT

72%

61.6%

n.s.

Alleles

 

N°134

N°256

 
 

G

(79/134) 59%

(160/256) 63%

n.s.

 

T

(55/134) 41%

(94/256) 37%

n.s.

  

Normotensives n. 38

Hypertensives n. 107

p <

T786C

TT

(8/38) 21%

(25/107) 23%

n.s.

 

TC

(19/38) 50%

(51/107) 48%

n.s.

 

CC

(11/38) 29%

(31/107) 29%

n.s.

 

TC+CC

79%

78%

n.s.

Alleles

 

N°76

N°214

 
 

T

(35/76) 46%

(101/214) 47%

n.s.

 

C

(41/76)54%

(113/214) 53%

n.s.

  

Normotensives n. 31

Hypertensives n. 119

p <

introne 4

bb

(24/31) 77%

(86/119) 72.5%

n.s.

 

ba

(7/31) 23%

(30/119) 25%

n.s.

 

aa

(0/31) 0%

(3/119) 2.5%

0.005

 

ab+aa

23%

27.5%

n.s.

Alleles

 

N°62

N°238

 
 

b

(55/62) 89%

(202/238) 85%

n.s.

 

a

(7/62) 11%

(36/238) 15%

n.s.

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Immunity & Ageing

ISSN: 1742-4933

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