Skip to main content

Advertisement

Table 3 Genotype frequency distribution of the three polymorphisms

From: Endothelial nitric oxide synthase gene polymorphisms and cardiovascular damage in hypertensive subjects: an Italian case-control study

   Normotensives n. 67 Hypertensives n. 127 p<
G894T GG (19/67) 28% (45/127) 35.4% n.s.
  GT (41/67) 61% (70/127) 55.1% n.s.
  TT (7/67) 11% (12/127) 9.5% n.s.
  GT+TT 72% 61.6% n.s.
Alleles   N°134 N°256  
  G (79/134) 59% (160/256) 63% n.s.
  T (55/134) 41% (94/256) 37% n.s.
   Normotensives n. 38 Hypertensives n. 107 p <
T786C TT (8/38) 21% (25/107) 23% n.s.
  TC (19/38) 50% (51/107) 48% n.s.
  CC (11/38) 29% (31/107) 29% n.s.
  TC+CC 79% 78% n.s.
Alleles   N°76 N°214  
  T (35/76) 46% (101/214) 47% n.s.
  C (41/76)54% (113/214) 53% n.s.
   Normotensives n. 31 Hypertensives n. 119 p <
introne 4 bb (24/31) 77% (86/119) 72.5% n.s.
  ba (7/31) 23% (30/119) 25% n.s.
  aa (0/31) 0% (3/119) 2.5% 0.005
  ab+aa 23% 27.5% n.s.
Alleles   N°62 N°238  
  b (55/62) 89% (202/238) 85% n.s.
  a (7/62) 11% (36/238) 15% n.s.