Figure 2

Heatmap of gene-expression of inflammatory markers. Green indicates repressed mRNA levels and red elevated levels. Intensities are normalized for each gene in each row. Samples and genes are grouped according to their similarity in profile, included is Nf-κB activity in the first row. The dendrogram reveals distinct clusters preferentially grouping cytokines, chemokines and interferon related molecules, specifically expressed in each cell strain. Samples of young donors are distinct from the group of older donors, and the samples of the 68 and 86 old donors are distinct within the group of older donors.