Table 1 List of inflammatory genes. Given are accession numbers of genes, fold changes and p-values between the group of older and young donors, a Pearson correlation coefficient (R) expressing similarity to the NF-κB profile as seen in Figure 1, and a description of genes.
Accession ID | Fold | p | R | Description |
|---|---|---|---|---|
NM_001733 | 2.3 | 0.023 | 0.74 | complement component 1, r subcomponent (C1R) |
NM_005438 | 2.0 | 0.033 | 0.71 | FOS-like antigen 1 (FOSL1) |
NM_000732 | 2.0 | 0.012 | 0.69 | CD3D antigen, delta polypeptide (TiT3 complex) (CD3D) |
NM_000586 | 4.6 | 0.020 | 0.68 | interleukin 2 (IL2) |
NM_004591 | 2.0 | 0.068 | 0.65 | chemokine (C-C motif) ligand 20 (CCL20) |
NM_005218 | 2.1 | 0.066 | 0.61 | defensin, beta 1 (DEFB1) |
NM_002993 | 2.0 | 0.097 | 0.58 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) (CXCL6) |
NM_003034 | 2.8 | 0.040 | 0.58 | sialyltransferase 8A (GD3 synthase) (SIAT8A) |
NM_002127 | 3.5 | 0.104 | 0.56 | HLA-G histocompatibility antigen, class I, G (HLA-G) |
NM_006644 | 2.6 | 0.102 | 0.52 | heat shock 105 kDa/110 kDa protein 1 (HSPH1) |
NM_080741 | 6.1 | 0.093 | 0.49 | sialidase 4 (NEU4) |
NM_002089 | 2.4 | 0.020 | 0.46 | chemokine (C-X-C motif) ligand 2 (CXCL2) |
NM_001928 | 5.6 | 0.094 | 0.45 | D component of complement (adipsin) (DF) |
NM_001937 | 2.2 | 0.017 | 0.41 | dermatopontin (DPT) |
NM_000634 | 4.3 | 0.068 | 0.39 | interleukin 8 receptor, alpha (IL8RA) |
NM_004887 | 3.5 | 0.047 | 0.38 | chemokine (C-X-C motif) ligand 14 (CXCL14) |
NM_024298 | 6.8 | 0.023 | 0.30 | leukocyte receptor cluster (LRC) member 4 (LENG4) |
NM_002416 | 3.6 | 0.068 | 0.22 | chemokine (C-X-C motif) ligand 9 (CXCL9) |
NM_006573 | 3.3 | 0.040 | 0.17 | tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B) |
NM_000575 | 2.7 | 0.033 | 0.17 | interleukin 1, alpha (IL1A) |
NM_003641 | 2.0 | 0.088 | 0.13 | interferon induced transmembrane protein 1 (9–27) (IFITM1) |
NM_000888 | 3.2 | 0.042 | 0.09 | integrin, beta 6 (ITGB6) |
NM_005521 | 2.0 | 0.094 | 0.06 | T-cell leukemia, homeobox 1 (TLX1) |
NM_004031 | 2.0 | 0.064 | 0.05 | interferon regulatory factor 7 (IRF7), transcript variant d |
NM_000716 | 2.2 | 0.085 | 0.05 | complement component 4 binding protein, beta (C4BPB) |
NM_007112 | 4.7 | 0.073 | 0.04 | thrombospondin 3 (THBS3) |
NM_182764 | 3.4 | 0.061 | 0.04 | engulfment and cell motility 2 (ELMO2), transcript variant 3 |
NM_207517 | 2.7 | 0.041 | 0.01 | ADAMTS-like 3 (ADAMTSL3) |
NM_148962 | 4.8 | 0.083 | -0.03 | oxoeicosanoid (OXE) receptor 1 (OXER1) |
NM_002427 | 5.1 | 0.093 | -0.11 | matrix metalloproteinase 13 (collagenase 3) (MMP13) |
NM_000570 | 3.3 | 0.094 | -0.15 | Fc fragment of IgG, low affinity IIIb, receptor for (CD16) (FCGR3B) |
NM_000577 | 2.7 | 0.116 | -0.19 | interleukin 1 receptor antagonist (IL1RN), transcript variant 3 |
NM_000603 | 2.4 | 0.088 | -0.21 | nitric oxide synthase 3 (endothelial cell) (NOS3) |
NM_002177 | 2.3 | 0.127 | -0.33 | interferon, omega 1 (IFNW1) |