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Table 2 Plasma retinoic acid and retinol concentrations at basal state (T0) and after supplementation with 13-cis-retinoic acid (T1)

From: Neutrophils are immune cells preferentially targeted by retinoic acid in elderly subjects

 

Young adults

Elderly

ANOVA

 

T0

T1

T0

T1

 

13-cis-retinoic acid (mg/l)

1.30 ± 0.08

202.61 ± 20

1.43 ± 0.07

149.95 ± 8.7

A, N, I

Retinol (μM)

2.76 ± 0.11

2.53 ± 0.09

3.14 ± 0.13

3.12 ± 0.15

A

  1. X ± SEM; n = 20 subjects per group. Two-way repeated-measures ANOVA was performed to discriminate among the effects of age (A; p < 0.05), nutritional treatment (N; p < 0.05) and their interaction (I; p < 0.05).
  2. For retinol, no significant interaction was found, and so comparison of marginal means was carried out, which indicated a significant effect of age (young: 2.64 ± 0.07 μM vs elderly: 3.13 ± 0.09 μM).
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Immunity & Ageing

ISSN: 1742-4933

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