Table 1 Subject characteristics of the b240 and placebo groups before and after the 12-week study
| Â | Pre-intervention | test | Post-intervention | test | ||
|---|---|---|---|---|---|---|
| Â | Placebo group | b240 group2 | P value | Placebo group | b240 group2 | P value |
Number of subjects (male/female) | 35 (9/26) | 38 (10/28) | Â | Â | Â | Â |
Age (y) | 71 ± 5 | 71 ± 5 | 0.846 |  |  |  |
Height (cm) | 155 ± 8 | 154 ± 6 | 0.497 | - | - |  |
Body weight (kg) | 55.3 ± 8.7 | 55.5 ± 6.8 | 0.916 | - | - |  |
BMI (kg/m2) | 22.9 ± 2.8 | 23.4 ± 2.5 | 0.447 | - | - |  |
Serum cortisol (μg/dL) | 12.0 ± 3.6 | 11.3 ± 3.6 | 0.403 | 11.3 ± 3.2 | 10.9 ± 4.6 | 0.721 |
Saliva chromogranin A/total protein ratio | 7.7 ± 5.1 | 9.7 ± 7.5 | 0.186 | 9.1 ± 7.3 | 9.2 ± 6.0 | 0.920 |
POMS1(points) | Â | Â | Â | Â | Â | Â |
   Tension-Anxiety | 48 ± 8 | 50 ± 10 | 0.289 | 48 ± 8 | 49 ± 9 | 0.751 |
   Depression-Dejection | 52 ± 10 | 53 ± 11 | 0.900 | 51 ± 10 | 51 ± 10 | 0.727 |
   Anger-Hostility | 51 ± 10 | 51 ± 8 | 0.999 | 49 ± 8 | 49 ± 9 | 0.796 |
   Vigor | 51 ± 7 | 53 ± 8 | 0.193 | 51 ± 9 | 53 ± 8 | 0.344 |
   Fatigue | 50 ± 9 | 52 ± 10 | 0.301 | 51 ± 10 | 52 ± 11 | 0.583 |
   Confusion | 51 ± 8 | 51 ± 11 | 0.963 | 50 ± 10 | 52 ± 9 | 0.516 |
Energy expenditure (kcal/day) | 1900 ± 327 | 1939 ± 296 | 0.591 | 1959 ± 335 | 1969 ± 298 | 0.892 |
Energy intake (kcal/day) | 2003 ± 525 | 1948 ± 620 | 0.685 | 2008 ± 607 | 1934 ± 653 | 0.618 |
   Protein/Total energy intake (%) | 16.9 ± 3.6 | 16.8 ± 2.7 | 0.883 | 16.8 ± 2.5 | 16.5 ± 2.8 | 0.644 |
   Fat/Total energy intake (%) | 28.6 ± 5.1 | 28.4 ± 5.1 | 0.881 | 28.7 ± 4.7 | 28.0 ± 5.4 | 0.568 |
   Carbohydrate/Total energy intake (%) | 51.2 ± 6.8 | 52.3 ± 5.8 | 0.444 | 51.5 ± 6.3 | 52.8 ± 5.7 | 0.385 |