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Table 2 SIgA secretion rate, SIgA concentration, and saliva flow rate in the b240 and placebo groups

From: Oral intake of Lactobacillus pentosus strain b240 accelerates salivary immunoglobulin A secretion in the elderly: A randomized, placebo-controlled, double-blind trial

 

Placebo group

 

Week 0

Week 2

Week 4

Week 6

Week 8

Week 10

Week 12

n

70

68

66

64

62

60

60

SIgA secretion rate2(μg/5 min)

319 ± 16

337 ± 21

333 ± 20

343 ± 21

348 ± 23

363 ± 22

334 ± 20

SIgA concentration (μg/mL)

173 ± 13

170 ± 11

161 ± 12

159 ± 11

157 ± 11

165 ± 12

154 ± 11

Saliva flow rate (mL/5 min)

2.5 ± 0.2

2.4 ± 0.2

2.7 ± 0.2

2.7 ± 0.2

2.8 ± 0.2

2.8 ± 0.2

2.9 ± 0.2

 

b240 group 1

 

Week 0

Week 2

Week 4

Week 6

Week 8

Week 10

Week 12

n

76

75

70

72

62

70

66

SIgA secretion rate2(μg/5 min)

297 ± 14

330 ± 20

357 ± 23

364 ± 27

366 ± 30

352 ± 23

359 ± 24

SIgA concentration (μg/mL)

147 ± 8

165 ± 10

156 ± 9

149 ± 11

134 ± 8

144 ± 8

149 ± 9

Saliva flow rate (mL/5 min)

2.3 ± 0.1

2.3 ± 0.2

2.6 ± 0.2

2.9 ± 0.2

3.0 ± 0.2

2.8 ± 0.2

2.7 ± 0.2

  1. Mean ± SEM; n, number of saliva sample; SIgA; secretory immunoglobulin A.
  2. 14 × 109 cells of heat-killed L. pentosus strain b240 per day for 12 weeks.
  3. 2SIgA secretion rate, which was calculated by multiplying SIgA concentration by saliva flow rate.
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Immunity & Ageing

ISSN: 1742-4933

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