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Table 1 Cell counts, plasma concentration of acute phase proteins and pro-inflammatory cytokines.

From: Transcriptomic biomarkers of the response of hospitalized geriatric patients with infectious diseases

     Benjamini
  HA (m±SD) AIA (m±SD) AIC (m±SD) AIA vs AIC AIA vs HA AIC vs HA
Cell counts (nb/μL)  
Lymphocytes 1531.76 ± 464.12 1086.58 ± 417.70 1442.65 ± 459.67 p < 0.001 p < 0.001 p < 0.001
Leucocytes 5975.76 ± 998.45 10601.16 ± 4623.98 8083.78 ± 2379.13 p < 0.001 p < 0.001 p < 0.001
Neutrophils 3762.94 ± 891.50 8734.72 ± 4284.35 5702.68 ± 2040.11 p < 0.001 p < 0.001 p < 0.001
Acute phase proteins  
Albumin (mg/dL) 4270.67 ± 443.31 2982.42 ± 483.71 ND   p < 0.001  
Prealbumin (mg/dL) 26.00 ± 4.74 10.69 ± 4.61 ND   p < 0.001  
CRP (mg/dL) 0.26 ± 0.41 18.34 ± 9.24 2.50 ± 3.45 p < 0.001 p < 0.001 p < 0.001
D-dimer (ng/mL) 647.22 ± 430.54 2442.90 ± 1692.26 1838.14 ± 1125.11 p < 0.05 p < 0.001 p < 0.05
Fibrinogen (mg/dL) 392.81 ± 65.54 752.09 ± 242.97 586.22 ± 172.04 p < 0.01 p < 0.001 p < 0.005
Pro-inflammatory cytokines  
IL6 (pg/mL) 14.01 ± 26.95 121.84 ± 98.73 56.28 ± 71.23 p < 0.001 p < 0.005 p < 0.001
IL10 (pg/mL) 1.15 ± 3.67 17.95 ± 109.00 ND   p < 0.001  
TNF alpha (pg/mL) 22.80 ± 12.57 52.30 ± 45.88 ND   p < 0.005  
  1. Values are expressed as mean ± SD. CRP: C-reactive protein; ND: Not Determined; Healthy Aged (HA); Aged patients with Infectious diseases in Acute phase (AIA); Aged patients with Infectious diseases in Convalescence phase (AIC).