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Table 1 Cell counts, plasma concentration of acute phase proteins and pro-inflammatory cytokines.

From: Transcriptomic biomarkers of the response of hospitalized geriatric patients with infectious diseases

    

Benjamini

 

HA (m±SD)

AIA (m±SD)

AIC (m±SD)

AIA vs AIC

AIA vs HA

AIC vs HA

Cell counts (nb/μL)

 

Lymphocytes

1531.76 ± 464.12

1086.58 ± 417.70

1442.65 ± 459.67

p < 0.001

p < 0.001

p < 0.001

Leucocytes

5975.76 ± 998.45

10601.16 ± 4623.98

8083.78 ± 2379.13

p < 0.001

p < 0.001

p < 0.001

Neutrophils

3762.94 ± 891.50

8734.72 ± 4284.35

5702.68 ± 2040.11

p < 0.001

p < 0.001

p < 0.001

Acute phase proteins

 

Albumin (mg/dL)

4270.67 ± 443.31

2982.42 ± 483.71

ND

 

p < 0.001

 

Prealbumin (mg/dL)

26.00 ± 4.74

10.69 ± 4.61

ND

 

p < 0.001

 

CRP (mg/dL)

0.26 ± 0.41

18.34 ± 9.24

2.50 ± 3.45

p < 0.001

p < 0.001

p < 0.001

D-dimer (ng/mL)

647.22 ± 430.54

2442.90 ± 1692.26

1838.14 ± 1125.11

p < 0.05

p < 0.001

p < 0.05

Fibrinogen (mg/dL)

392.81 ± 65.54

752.09 ± 242.97

586.22 ± 172.04

p < 0.01

p < 0.001

p < 0.005

Pro-inflammatory cytokines

 

IL6 (pg/mL)

14.01 ± 26.95

121.84 ± 98.73

56.28 ± 71.23

p < 0.001

p < 0.005

p < 0.001

IL10 (pg/mL)

1.15 ± 3.67

17.95 ± 109.00

ND

 

p < 0.001

 

TNF alpha (pg/mL)

22.80 ± 12.57

52.30 ± 45.88

ND

 

p < 0.005

 
  1. Values are expressed as mean ± SD. CRP: C-reactive protein; ND: Not Determined; Healthy Aged (HA); Aged patients with Infectious diseases in Acute phase (AIA); Aged patients with Infectious diseases in Convalescence phase (AIC).
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Immunity & Ageing

ISSN: 1742-4933

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