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Table 2 Genes differentially expressed in PMBC of Aged patients with Infectious diseases in Acute phase (AIA) patients (n = 39) versus healthy aged (HA) probands (n = 28).

From: Transcriptomic biomarkers of the response of hospitalized geriatric patients with infectious diseases

Gene Symbol Gene Name Accession Number AIA/HA ratio Benjamini
BCL2 B-cell CLL/lymphoma 2 NM_000633.1 0.58 p < 0.001
CASP8 Caspase 8, apoptosis-related cysteine peptidase X98172.1 0.66 p < 0.001
CCL5 Chemokine (C-C motif) ligand 5 NM_002985.1 0.71 p < 0.001
CD28 CD28 antigen (Tp44) NM_006139.1 0.61 p < 0.005
CD69 CD69 antigen (p60, early T-cell activation antigen) NM_001781.1 0.44 p < 0.001
DDIT3 DNA-damage-inducible transcript 3 S40706.1 0.76 p < 0.01
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 D49547.1 0.76 p < 0.001
EGR3 Early growth response 3 NM_004430.1 0.42 p < 0.05
LCK Lymphocyte-specific protein tyrosine kinase NM_005356.2 0.58 p < 0.001
CLU Clusterin J02908.1 1.79 p < 0.001
CTSD Cathepsin D (lysosomal aspartyl peptidase) M11233.1 1.50 p < 0.001
CTSZ Cathepsin Z AF136273.1 1.33 p < 0.05
GPX1 Glutathione peroxidase 1 M21304.1 1.21 p < 0.05
HMOX1 Heme oxygenase (decycling) 1 NM_002133.1 1.57 p < 0.001
IL10RB Interleukin 10 receptor, beta NM_000628.3 1.39 p < 0.001
IL1R1 Interleukin 1 receptor, type I NM_000877.2 1.48 p < 0.05
IL1R2 Interleukin 1 receptor, type II U74649.1 2.34 p < 0.001
PRDX6 Peroxiredoxin 6 NM_004905.1 1.23 p < 0.005
PSMD1 Proteasome (prosome, macropain) 26 S subunit, non-ATPase, 1 NM_002807.1 1.24 p < 0.001
SERPINB2 Serpin peptidase inhibitor, clade B (ovalbumin), member 2 J02685.1 2.17 p < 0.005
SOD2 Superoxide dismutase 2, mitochondrial NM_000636.1 1.53 p < 0.001
TIMP1 TIMP metallopeptidase inhibitor 1 NM_003254.1 1.71 p < 0.001
TIMP2 TIMP metallopeptidase inhibitor 2 NM_003255.2 1.59 p < 0.001
TNFRSF1A Tumor necrosis factor receptor superfamily, member 1A NM_001065.2 1.45 p < 0.001
  1. Statistical analysis was carried out with the Mann-Whitney test.