Table 2 Risk of any dementia and Alzheimer Disease by quartiles of plasma total homocysteine and serum folate

Quartiles of plasma total homocysteine, μmol/L

< 10.1

1.00

1.00

10.1 to 12.5

1.73 [0.87 – 3.46]

0.117

2.43 [0.96 – 6.13]

0.062

12.6 to 15.0

2.02 [0.96 – 4.23]

0.060

2.43 [0.96 – 6.13]

0.060

> 15.00

3.55 [1.72 – 7.29]

0.001

4.33 [1.73 – 10.8]

0.002

Quartiles of serum folate, nmol/L

< 8.9

2.22 [1.21 – 4.05]

0.010

2.04 [1.02 – 4.09]

0.045

8.9 to 11.8

1.83 [1.00 – 3.34]

0.050

1.30 [0.62 – 2.72]

0.484

11.9 to 15.2

1.16 [0.60 – 2.24]

0.064

0.66 [0.29 – 1.54]

0.340

> 15.2

1.00

1.00