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Table 1 Study population characteristics

From: Differential effects of age, cytomegalovirus-seropositivity and end-stage renal disease (ESRD) on circulating T lymphocyte subsets

  

ESRD patients

healthy controls

P-value

number of individuals

 

139

111

 

age (yrs)*

 

46 (18-78)

50 (21-78)

0.13

sexe (male)

 

75%

48%

< 0.01

CMV seropositive

 

53%

59%

0.10

CMV IgG (AU/mL)*

 

54 (6-252)

47 (6-199)

0.54

underlying kidney disease

    
 

hypertensive nephropathy

36.6%

  
 

primary glomerulopathy

20.1%

  
 

diabetic nephropathy

7.5%

  
 

polycystic kidney disease

0.0%

  
 

other

30.6%

  
 

unknown

5.2%

  

type of renal replacement therapy

    
 

hemodialysis

41%

  
 

peritoneal dialysis

24.6%

  
 

previous kidney transplantation

4.5%

  
 

none

29.9%

  
  1. * values are median (range), percentages are means.
  2. Distribution of gender and CMV-seropositivity within the healthy donor and ESRD patients was tested using the Chi-square test. Gender did not significantly alter the composition of T lymphocyte subsets.
  3. Comparison between the healthy donors and ESRD patients with respect to age, CMV-serology was tested using the Mann-Whitney U-test
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Immunity & Ageing

ISSN: 1742-4933

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