Table 2 Genotype distribution and allele frequency of VEGF SNP (rs 699947) from Offs, CTR and AMI
From: Pro-inflammatory genetic profile and familiarity of acute myocardial infarction
VEGF | CC (n) % | CA (n) % | AA (n) % | C carriers (n) % | A carriers (n) % |
|---|---|---|---|---|---|
Offs (n = 154) | (97) 63 | (42) 27.3 | (15) 9.7 | (139) 90.3 | (58) 37.7 |
CTR (n = 291) | (119) 40.9 | (127) 43.6 | (45) 15.5 | (246) 84.5 | (172) 59.1 |
AMI (n = 257) | (167) 65 | (78) 30.4 | (12) 4.7 | (245) 95.3 | (90) 35 |
Offs vs CTR | χ2 = 19.680, p = 0.0001; CC carriers vs non-CC carriers: χ2 = 19.745, p = 0.0001; A carriers χ2 = 18.545, p = 0.0001. | ||||
AMI vs CTR | χ2 = 36.906, p = 0.0001; CC carriers vs non-CC carriers: χ2 = 31.796, p = 0.0001; OR = 2.689 (CI: 1.900-3.806); AA carriers vs non-AA carriers: χ2 = 16.943, p = 0.0001; OR = 0.269 (CI: 0.139-0.521); C carriers χ2 = 17.063, p = 0.0001; OR = 3.735 (CI: 1.929-7.232); A carriers χ2 = 31.733, p = 0.0001; OR = 0.373 (CI: 0.264-0.527). | ||||
Offs vs AMI | χ2 = 4.141, p = 0.126. | ||||