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Table 4 SNP IFN-γ (rs 2430561) genotype distribution and allele frequency from Offs, CTR and AMI.

From: Pro-inflammatory genetic profile and familiarity of acute myocardial infarction

IFN-γ TT (n) % TA (n) % AA (n) % T carr (n) % A carr (n) %
Offs (n = 153) (24) 15.7 (88) 57.5 (41) 26.8 (112) 73.2 (129) 84.3
CTR (n = 268) (82) 30.6 (111) 41.4 (75) 28 (193) 72.0 (186) 69.4
AMI (n = 240) (58) 24.2 (96) 40 (86) 35.8 (154) 64.2 (182) 75.8
Offs vs CTR χ2 = 13.990, p = 0.001; TT carriers vs non-TT carriers: χ2 = 11.070, p = 0.001; A carriers χ2 = 11.495, p = 0.001
AMI vs CTR χ2 = 4.423, p = 0.110
Offs vs AMI χ2 = 11.704, p = 0.003; TT carriers vs non-TT carriers: χ2 = 4.380, p = 0.036; OR = 1.761 (CI: 1.032-3.002); A carriers χ2 = 4.070, p = 0.044; OR = 0.584 (CI: 0.345-0.988).