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Table 4 SNP IFN-γ (rs 2430561) genotype distribution and allele frequency from Offs, CTR and AMI.

From: Pro-inflammatory genetic profile and familiarity of acute myocardial infarction

IFN-γ

TT (n) %

TA (n) %

AA (n) %

T carr (n) %

A carr (n) %

Offs (n = 153)

(24) 15.7

(88) 57.5

(41) 26.8

(112) 73.2

(129) 84.3

CTR (n = 268)

(82) 30.6

(111) 41.4

(75) 28

(193) 72.0

(186) 69.4

AMI (n = 240)

(58) 24.2

(96) 40

(86) 35.8

(154) 64.2

(182) 75.8

Offs vs CTR

χ2 = 13.990, p = 0.001; TT carriers vs non-TT carriers: χ2 = 11.070, p = 0.001; A carriers χ2 = 11.495, p = 0.001

AMI vs CTR

χ2 = 4.423, p = 0.110

Offs vs AMI

χ2 = 11.704, p = 0.003; TT carriers vs non-TT carriers: χ2 = 4.380, p = 0.036; OR = 1.761 (CI: 1.032-3.002); A carriers χ2 = 4.070, p = 0.044; OR = 0.584 (CI: 0.345-0.988).