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Table 2 CD4+ T cells and subsets in the 4 BMI categories of young subjects

From: Nutritional status influences peripheral immune cell phenotypes in healthy men in rural Pakistan

 

BMI Category

p-value

 

NW

OB

OW

UW

OB-NW

OW-NW

UW-NW

CD4+

37.2 (6.71)

24.3 (11.51)

24.4 (11.60)

26.8 (10.11)

0.0014

0.316

0.180

CD28+CD27+

54.3 (11.12)

45.3 (14.19)

45.1 (13.72)

54.1 (15.81)

0.2339

0.2213

0.2121

CD28-CD27-

12.3 (6.11)

14.1 (10.61)

14.7 (8.21)

15.0 (7.43)

0.9090

0.8150

0.7434

CD45RO+CD27-

21.2 (15.21)

17.9 (9.21)

16.1 (12.45)

22.5 (14.27)

0.8616

0.6492

0.9892

CD45RO-CD27+

27.6 (16.12)

30.9 (15.9)

31.8 (15.31)

30.3 (15.11)

0.9159

0.8439

0.4312

CD45RA+CD27+

33.6 (14.21)

27.1 (8.81)

19.6 (16.61)

21.8 (19.71)

0.5412

0.0466

0.1139

CD45RA-CD27-

14.1 (9.31)

36.3 (10.71)

42.1 (24.40)

54.7 (35.62)

0.3971

0.0072

0.0032

CD45RO+CD28-

8.8 (4.71)

9.5 (7.32)

6.2 (3.11)

12.6 (4.72)

0.9784

0.4521

0.1656

CD45RO-CD28+

44.4 (14.81)

31.2 (14.12)

38.1 (17.51)

30.9 (8.11)

0.5733

0.5449

0.0511

CD45RA+CD28+

33.8 (17.81)

27.1 (20.62)

17.5 (25.01)

31.3 (14.21)

0.7261

0.1053

0.1797

CD45RA-CD28-

16.7 (12.71)

19.2 (20.21)

23.4 (21.60)

23.4 (14.32)

0.9682

0.6445

0.6512

TRegs

3.9 (4.53)

5.9 (5.72)

4.8 (3.90)

3.2 (4.31)

0.5819

0.9172

0.9713

CD28+CD27+KLRG1-CD57-

37.1 (18.10)

34.6 (16.61)

30.1 (15.61)

22.4 (20.31)

0.9713

0.6355

0.1065

CD28-CD27-KLRG1+CD57+

0.6 (0.90)

0.6 (1.32)

1.0 (1.51)

2.3 (1.10)

0.5436

0.8415

0.0028

  1. Significant Dunnett’s test (p < 0.05) comparing CD4+ T subsets with the reference group. The reference group defined as having BMI, 18.5–24.9.OB, Obese; OW, Overweight; NW, Normal Weight; UW, Underweight. The values are means (SD).